肝细胞癌肝移植术后肿瘤复发的危险因素与防治策略

郑卫萍; 沈中阳

doi:10.3969/j.issn.1001-5256.2019.11.003

肝细胞癌肝移植术后肿瘤复发的危险因素与防治策略

DOI: 10.3969/j.issn.1001-5256.2019.11.003

天津市第一中心医院器官移植中心

基金项目:

天津市器官移植临床医学研究中心项目(15ZXLCSY00070)；中国医学科学院中央级公益性科研院所基本科研业务费专项资金(2019PT320016)；

详细信息

中图分类号: R735.7
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出版历程
- 收稿日期: 2019-10-07
- 出版日期: 2019-11-20

Risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma and related control strategies

Center of Organ Transplantation,Tianjin First Central Hospital

Research funding:

摘要

摘要: 肝细胞癌肝移植术后肿瘤的复发是造成患者和移植物存活率显著下降的主要原因。影响肝移植术后肿瘤复发的危险因素主要包括肿瘤的病理和生物学特性、受者相关因素、供者和供肝相关因素、手术相关因素等。免疫抑制方案的管理以及多种辅助治疗有助于预防肿瘤复发。针对肝细胞癌肝移植患者,如何早期识别肿瘤复发的危险因素并进行综合防治值得进一步探讨。
- 癌,肝细胞 /
- 肝移植 /
- 肿瘤复发,局部 /
- 危险因素 /
- 二级预防
Abstract: Tumor recurrence after liver transplantation for hepatocellular carcinoma is the main cause of significant reductions in the survival rates of patients and grafts. Risk factors for tumor recurrence after liver transplantation include pathological and biological features,factors associated with the recipient,factors associated with the donor and donor liver,and surgery-related factors. Immunosuppression regimen and various adjuvant therapies may help to prevent tumor recurrence. For patients undergoing liver transplantation for hepatocellular carcinoma,further studies are needed to investigate early identification of risk factors for tumor recurrence and related comprehensive prevention and treatment measures.
- carcinoma,hepatocellular /
- liver transplantation /
- neoplasm recurrence,local /
- risk factors /
- secondary prevention

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参考文献(50)

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