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陕西地区肝衰竭病因构成及变迁特点分析

闫涛涛 李娟 付珊 张柔 任丹凤 朱丽 刘锦锋 何英利 赵英仁 张欣欣

闫涛涛, 李娟, 付珊, 张柔, 任丹凤, 朱丽, 刘锦锋, 何英利, 赵英仁, 张欣欣. 陕西地区肝衰竭病因构成及变迁特点分析[J]. 临床肝胆病杂志, 2020, 36(2): 387-390. DOI: 10.3969/j.issn.1001-5256.2020.02.031.
引用本文: 闫涛涛, 李娟, 付珊, 张柔, 任丹凤, 朱丽, 刘锦锋, 何英利, 赵英仁, 张欣欣. 陕西地区肝衰竭病因构成及变迁特点分析[J]. 临床肝胆病杂志, 2020, 36(2): 387-390. DOI: 10.3969/j.issn.1001-5256.2020.02.031.
Yan TaoTao, Li Juan, Fu Shan, Zhang Rou, Ren DanFeng, Zhu Li, Liu JinFeng, He YingLi, Zhao YingRen, Zhang XinXin. Composition and changing trend of the etiologies of liver failure in Shaanxi Province,China[J]. J Clin Hepatol, 2020, 36(2): 387-390. DOI: 10.3969/j.issn.1001-5256.2020.02.031.
Citation: Yan TaoTao, Li Juan, Fu Shan, Zhang Rou, Ren DanFeng, Zhu Li, Liu JinFeng, He YingLi, Zhao YingRen, Zhang XinXin. Composition and changing trend of the etiologies of liver failure in Shaanxi Province,China[J]. J Clin Hepatol, 2020, 36(2): 387-390. DOI: 10.3969/j.issn.1001-5256.2020.02.031.

陕西地区肝衰竭病因构成及变迁特点分析

DOI: 10.3969/j.issn.1001-5256.2020.02.031
基金项目: 

国家“十三五”传染病重大专项(2017ZX10202202-002-006); 国家自然科学基金(81670537); 西安交通大学第一附属医院青年科学创新基金(2018QN-02); 

详细信息
  • 中图分类号: R575.3

Composition and changing trend of the etiologies of liver failure in Shaanxi Province,China

Research funding: 

 

  • 摘要:

    目的探讨陕西地区肝衰竭的病因构成及变迁特点。方法回顾性收集2008年1月-2017年12月在西安交通大学第一附属医院住院的来自陕西省的975例肝衰竭患者的临床资料并进行分析。根据肝衰竭临床类型,分为急性肝衰竭(ALF)(n=115)、亚急性肝衰竭(SALF)(n=165)及慢加急性肝衰竭(ACLF)(n=695) 3组。计量资料多组间比较采用单因素方差分析,两组间比较采用t检验;计数资料组间比较采用χ2检验。结果 ALF的首要病因为药物(25. 22%,29/115),其次为HBV感染(21. 74%,25/115); SALF的首要病因为HBV感染(35. 15%,58/165),其次为药物(27. 27%,45/165); ACLF的首要病因为HBV感染(87. 19%,606/695),其次为酒精(3. 45%,24/695)。HBV感染、酒精性及药物性肝衰竭患者的年龄分布区间主要以20~60岁(595/689)、30~40岁(22/32)及30~70岁(67/89)为主。近5年HBV感染相关的肝衰竭比例较前5年显著下降(61. 52%vs81. 33%,χ...

     

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  • 收稿日期:  2019-09-02
  • 出版日期:  2020-02-20
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