循环游离DNA在肝癌和肝相关性寄生虫病中的应用进展

后亚军; 张灵强; 樊海宁

doi:10.3969/j.issn.1001-5256.2020.02.043

循环游离DNA在肝癌和肝相关性寄生虫病中的应用进展

DOI: 10.3969/j.issn.1001-5256.2020.02.043

1. 青海大学研究生院
2. 青海大学附属医院肝胆胰外科
3. 青海省包虫病重点研究实验室

基金项目:

青海省包虫病临床医学研究中心项目（2017-SF-L2）；

详细信息

中图分类号: R735.7;R53
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出版历程
- 收稿日期: 2019-09-20
- 出版日期: 2020-02-20

Research advances in circulating free DNA in liver cancer and liver-related parasitic diseases

Qinghai University Graduate School

Research funding:

摘要

摘要:
液体活检是一种新型非侵入性检测方法,也是指导精准医疗应用的主要分子检测方法。液体活检主要包括:循环游离DNA（cf-DNA）、循环肿瘤细胞（CTC）、外泌体（exosomes）等,尤其是cf-DNA正在成为一种有价值的分子检测工具,特别是在肝癌的早期检测、诊断方面,以及最近在寄生虫感染累及肝脏疾病中的临床应用。综述了cf-DNA在肝癌和肝相关性寄生虫病中的临床应用。
- 肝肿瘤 /
- 寄生虫病 /
- 循环游离DNA
Abstract:
Liquid biopsy is a new noninvasive detection method and is also the main molecular detection method to guide the application of precision medicine. Liquid biopsy mainly includes the measurement of circulating free DNA( cf-DNA),circulating tumor cells,and exosomes,and in particular,cf-DNA is becoming a valuable molecular detection tool,especially in the early detection and diagnosis of liver cancer and parasitic infections involving the liver. This article reviews the clinical application of cf-DNA in liver cancer and liver-related parasitic diseases.
- liver neoplasms /
- parasitic diseases /
- circulating free DNA

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参考文献(40)

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