65例新疆地区哈萨克族原发性胆汁性胆管炎的临床特征分析

赵凤丛; 刘兰; 张永萍; 马安林

doi:10.3969/j.issn.1001-5256.2020.05.031

65例新疆地区哈萨克族原发性胆汁性胆管炎的临床特征分析

DOI: 10.3969/j.issn.1001-5256.2020.05.031

1. 新疆维吾尔自治区人民医院感染性疾病科
2. 中日友好医院感染性疾病科

基金项目:

中日友好医院院级课题（2015-38）；

详细信息

中图分类号: R575.22
计量
- 文章访问数: 711
- HTML全文浏览量: 19
- PDF下载量: 140
- 被引次数: 0
出版历程
- 出版日期: 2020-05-20

Clinical characteristics of primary biliary cholangitis in Kazakhs, Xinjiang, China: An analysis of 65 cases

Department of Infectious Diseases, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China

Research funding:

摘要

摘要:
<正>原发性胆汁性胆管炎（PBC）是一种具有遗传基础的慢性进展性胆汁淤积性肝病,患者早期主要表现为乏力、皮肤瘙痒等非特异性症状,随着疾病进展,逐渐出现黄疸、脾大、门静脉高压,最终发展为肝硬化、肝衰竭。PBC易合并多种自身免疫性疾病,如干燥综合征、系统性硬化症、类风湿关节炎和桥本甲状腺炎等。国际多项研究[1-2]均表明PBC呈全球性分布,并存
- 原发性胆汁性胆管炎 /
- 新疆[维吾尔自治区] /
- 疾病特征
- primary biliary cholangitis /
- Xinjiang /
- disease attributes

HTML全文

参考文献(20)

[1] CAREY EJ, ALI AH, LINDOR KD. Primary biliary cirrhosis[J].Lancet, 2015, 386(10003):1565-1575.

[2] BOONSTRA K, BEUERS U, PONSIOEN CY. Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis:A systematic review[J]. J Hepatol, 2012, 56(5):1181-1188.

[3] Chinese Society of Hepatology, Chinese Medical Association;Chinese Society of Gastroenterology, Chinese Medical Association; Chinese Society of Infectious Diseases, Chinese Medical Association. Consensus on diagnosis and treatment of primary biliary cirrhosis(also known as primary bile cholangitis)(2015)[J]. J Clin Hepatol, 2015, 31(12):1980-1988.(in Chinese）中华医学会肝病学分会，中华医学会消化病学分会，中华医学会感染病学分会．原发性胆汁性肝硬化（又名原发性胆汁性胆管炎）诊断和治疗共识（2015)[J]．临床肝胆病杂志，2015, 31(12):1980-1988.

[4] LINDOR K, BOWLUS C, BOYER J, et al. Primary biliary cholangitis:2018 practice guidance from the American Association for the Study of Liver Diseases[J]. Hepatology, 2019, 69(1):394-419.

[5] GATSELIS NK, ZACHOU K, LYGOURA V, et al. Geoepidemiology, clinical manifestations and outcome of primary biliary cholangitis in Greece[J]. Eur J Intern Med, 2017, 42:81-88.

[6] ZENG N, DUAN W, et al. Epidemiology and clinical course of primary biliary cholangitis in the Asia-Pacific region:A systematic review and meta-analysis[J]. Hepatol Int, 2019, 13:788.

[7] KOULENTAKI M, MANTAKA A, SIFAKI-PISTOLLA D, et al.Geoepidemiology and space-time analysis of primary biliary cirrhosis in Crete, Greece[J]. Liver Int, 2014, 34(7):e200-e207.

[8] SELMI C, MAYO MJ, BACH N, et al. Primary biliary cirrhosis in monozygotic and dizygotic twins:Genetics, epigenetics, and environment[J]. Gastroenterology, 2004, 127(2):485-492.

[9] ZHAO FC, ZHANG YP. Clinical characteristics of primary biliary cholangitis in 44 cases[J]. Xinjiang Med, 2019, 49(2):169-171,182.(in Chinese）赵凤丛，张永萍．44例原发性胆汁性胆管炎临床特征分析[J]．新疆医学，2019, 49(2):169-171, 182.

[10] AL-HARTHY N, KUMAGI T, COLTESCU C, et al. The specificity of fatigue in primary biliary cirrhosis:Evaluation of a large clinic practice[J]. Hepatology, 2010, 52(2):562-570.

[11] YAMAGIWA S, KAMIMURA H, TAKAMURA M, et al. Autoantibodies in primary biliary cirrhosis:Recent progress in research on the pathogenetic and clinical significance[J]. World J Gastroenterol, 2014, 20(10):2606-2612.

[12] KOUROUMALIS E, SAMONAKIS D, VOUMVOURAKI A. Biomarkers for primary biliary cholangitis:Current perspectives[J]. Hepat Med, 2018, 10:43-53.

[13] FLOREANI A, FRANCESCHET I, CAZZAGON N. Primary biliary cirrhosis:Overlaps with other autoimmune disorders[J].Semin Liver Dis, 2014, 34(3):352-360.

[14] WANG L, ZHANG FC, CHEN H, et al. Connective tissue diseases in primary biliary cirrhosis:A population-based cohort study[J]. World J Gastroenterol, 2013, 19(31):5131-5137.

[15] HEATHCOTE J. The clinical expression of primary biliary cirrhosis[J]. Semin Liver Dis, 1997, 17(1):23-33.

[16] CAMACHO PM, PETAK SM, BINKLEY N, et al. American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for the diagnosis and treatment of postmenopausal osteoporosis-2016[J]. Endocr Pract, 2016, 22(Suppl 4):1-42.

[17] GAO XS, ZHANG YN, LIU T, et al. Osteoporosis in patients with primary biliary cirrhosis[J/CD]. Chin J Liver Dis:Electronic Edition, 2018, 10(3):56-60.(in Chinese）高学松，张耀南，刘婷，等．原发性胆汁性肝硬化患者合并骨质疏松症临床研究[J/CD]．中国肝脏病杂志（电子版），2018, 10(3):56-60.

[18] GLASS LM, SU GL. Metabolic bone disease in primary biliary cirrhosis[J]. Gastroenterol Clin North Am, 2016, 45(2):333-343.

[19] GUAÑABENS N, CERDÁD, MONEGAL A, et al. Low bone mass and severity of cholestasis affect fracture risk in patients with primary biliary cirrhosis[J]. Gastroenterology, 2010, 138(7):2348-2356.

[20] BUERBUHAN H, TANG XJ, LIU HH, et al. Correlation between dietary habits and incidence of anemia among Kazakh pregnant women in Altay, Xinjiang[J]. Chin Prev Med, 2016,17(2):154-156.(in Chinese）布尔布汗·哈什肯别克，汤雪娟，刘海湖，等．新疆阿勒泰地区哈萨克族孕妇饮食习惯与贫血发生率相关性研究[J]．中国预防医学杂志，2016, 17(2):154-156.

施引文献

资源附件(0)

访问统计