中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

男性原发性胆汁性胆管炎合并抗富亮氨酸胶质瘤失活1蛋白抗体相关脑炎1例报告

刘曼 唐彤丹 刘永华 朱磊

引用本文:
Citation:

男性原发性胆汁性胆管炎合并抗富亮氨酸胶质瘤失活1蛋白抗体相关脑炎1例报告

DOI: 10.3969/j.issn.1001-5256.2020.05.035
详细信息
  • 中图分类号: R575.7;R742.9

A male case of primary biliary cholangitis with anti-leucine-rich glioma-inactivated 1 antibody-associated encephalitis: A case report 

  • 摘要:

    <正>原发性胆汁性胆管炎(PBC)是一种由免疫介导的、抗线粒体抗体阳性的小叶间胆管炎症性损伤的慢性胆汁淤积性疾病,是女性慢性肝病的一个非常重要的病因,极少数见于男性患者。抗富亮氨酸胶质瘤失活1蛋白(leucine-rich glioma inacti-vated-1, LGI1)抗体相关脑炎是自身免疫性脑炎(autoimmuneence phalitis, AE)的一种,多见于中老年男性,与癫痫有高度相

     

  • [1] SHIN YW, LEE ST, SHIN JW, et al. VGKC-complex/LGI1-antibody encephalitis:Clinical manifestations and response to immunotherapy[J]. J Neuroimmunol, 2013, 265(1-2):75-81.
    [2] BASTIAANSEN AEM, van SONDEREN A, TITULAER MJ. Autoimmune encephalitis with anti-leucine-rich glioma-inactivated 1or anti-contactin-associated protein-like 2 antibodies(formerly cal ed voltage-gated potassium channel-complex antibodies)[J]. Curr Opin Neurol, 2017, 30(3):302-309.
    [3] GUAN HZ, REN HT, CUI LY. Autoimmune encephalitis:An expanding frontier of neuroimmunology[J]. Chin Med J(Engl), 2016, 129(9):1122-1127.
    [4] XIA ZY, HAN T, MENG HJ. Early immunosuppression combined with ursodeoxycholic acid in the treatment of primary biliary cirrhosis[J]. Clin J Med Offic, 2020, 48(1):97-98,101.(in Chinese)夏志勇,韩涛,孟红军.早期免疫抑制联合熊去氧胆酸治疗原发性胆汁性肝硬化临床疗效[J].临床军医杂志,2020, 48(1):97-98, 101.
    [5] LAN RY, CHENG C, LIAN ZX, et al. Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis[J]. Hepatology, 2006, 43(4):729-737.
    [6] GAO XS, ZHANG YN, LIU T, et al. Osteoporosis in patients with primary biliary cirrhosis[J/CD]. Chin J Liver Dis(Electronic Edition), 2018, 10(3):56-60.(in Chinese)高学松,张耀南,刘婷,等.原发性胆汁性肝硬化患者合并骨质疏松症临床研究[J/CD].中国肝脏病杂志(电子版),2018, 10(3):56-60.
    [7] AGMON-LEVIN N, KOPILOV R, SELMI C, et al. Vitamin D in primary biliary cirrhosis, a plausible marker of advanced disease[J]. Immunol Res, 2015, 61(1-2):141-146.
    [8] WEISSERT R. Adaptive immunity is the key to the understanding of autoimmune and paraneoplastic inflammatory central nervous system disorders[J]. Front Immunol, 2017, 23(8):336.
    [9] DANNER OK, MATTHEWS LR, FRANCIS S, et al. Vitamin D3suppresses class II invariant chain peptide expression on activated-B-lymphocytes:A plausible mechanisms for downregulation on acute inflammatory conditions[J]. J Nutr Metab,2016, 2016:4280876.
  • 加载中
计量
  • 文章访问数:  679
  • HTML全文浏览量:  11
  • PDF下载量:  146
  • 被引次数: 0
出版历程
  • 出版日期:  2020-05-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回