CA19-9明显升高的IgG4相关性胆胰疾病1例报告

余乐乐; 熊芳; 闾军

doi:10.3969/j.issn.1001-5256.2020.05.039

CA19-9明显升高的IgG4相关性胆胰疾病1例报告

DOI: 10.3969/j.issn.1001-5256.2020.05.039

首都医科大学附属北京佑安医院肝病与肿瘤生物治疗科

基金项目:

十二五国家科技重大专项任务级课题（2014ZX10002002-001-002）；首都卫生发展科研专项项目（2018-1-2181）；首都临床特色应用研究（Z181100001718191）；北京市属医院科研培育项目（PX2019063）；

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中图分类号: R593.2;R57
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出版历程
- 出版日期: 2020-05-20

IgG4-related biliary and pancreatic diseases with significantly elevated CA19-9: A case report

Department of Hepatopathy and Cancer Biotherapy, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China

Research funding:

摘要

摘要:
<正>随着近年来IgG4相关性疾病（immunoglobulin G4 relatedsystemic disease,IgG4-RD）概念的提出,该类疾病以组织中大量IgG4阳性浆细胞浸润、纤维化及闭塞性静脉炎为主要病理特征,可以累及多种器官或组织[1]。IgG4相关性胆胰疾病主要包括IgG4相关性自身免疫性胰腺炎、IgG4相关性硬化性胆管炎等。部分IgG4相关性胆胰疾病患者可见CA19-9升高,但
- 免疫球蛋白G /
- 自身免疫疾病 /
- 胆道疾病 /
- 胰腺疾病
- immunoglobulin G /
- autoimmune diseases /
- biliary tract diseases /
- pancreatic diseases

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参考文献(5)

[1] NAKAZAWA T, ANDO T, HAYASHI K, et al. Diagnostic procedures for IgG4-related sclerosing cholangitis[J]. J Hepatobiliary Pancreat Sci, 2011, 18(2):127-136.

[2] HEGADE VS, SHERIDAN MB, HUGGETT MT. Diagnosis and management of IgG4-related disease[J]. Frontline Gastroenterol, 2019, 10(3):275-283.

[3] YONG HF, DONG X, WANG WS, et al. Computed tomography and magnetic resonance imaging features of IgG4-related pancreatitis[J]. Chin J Dig Surg, 2019, 18(7):689-697.(in Chinese）雍惠芳，董雪，王文森，等．IgG4相关性胰腺炎CT和MRI检查的影像学特征[J]．中华消化外科杂志，2019, 18(7):689-697.

[4] MORRIS-STIFF G, TELI M, JARDINE N, et al. CA19-9 antigen levels can distinguish between benign and malignant pancreaticobiliary disease[J]. Hepatobiliary Pancreat Dis Int,2009, 8(6):620-626.

[5] TAN L, GUAN X, ZENG T, et al. The significance of serum IgG4 and CA19-9, autoantibodies in diagnosis and differential diagnosis of IgG4-related sclerosing cholangitis[J].Scand J Gastroenterol, 2018, 53(2):206-211.

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