Research advances in conversion therapy for primary liver cancer
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摘要:
根治性肝切除及肝移植术是改善原发性肝癌远期预后的最佳选择,然而我国大部分肝癌患者确诊时已丧失手术治疗机会。因此,转化治疗成为提高中晚期肝癌患者生存率的研究热点。简述了肝癌转化治疗的评估内容,并归纳了目前不可切除性肝癌的转化治疗方案。随着对原发性肝癌及个体化治疗的进一步了解,精准医疗联合多学科诊疗团队制定出个体化的转化治疗方案,认为能够有效提高中晚期肝癌患者手术切除率及治疗效果,改善远期预后。
Abstract:Radical hepatectomy and liver transplantation are the best choices to improve the long-term prognosis of patients with primary liver cancer;however,most of the patients in China have lost the opportunity for surgical treatment at the time of confirmed diagnosis.Therefore,conversion therapy has become a research hotspot in improving the survival rate of patients with advanced liver cancer.This article briefly describes the evaluation of conversion therapy for liver cancer and summarizes the current conversion treatment regimens for unresectable liver cancer.With the deepening of the understanding of primary liver cancer and individualized treatment,the group of precise treatment combined with multidisciplinary diagnosis and treatment develops the regimens for individualized conversion therapy,which is considered to effectively improve the surgical resection rate,treatment outcome,and long-term prognosis of patients with advanced liver cancer.
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Key words:
- liver neoplasms /
- therapeutics /
- treatment outcome
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