microRNA在胆囊癌中的作用

成亚飞; 王斌; 王世明

doi:10.3969/j.issn.1001-5256.2020.08.049

microRNA在胆囊癌中的作用

DOI: 10.3969/j.issn.1001-5256.2020.08.049

1. 山西医科大学研究生院
2. 山西医科大学第一医院肝胆胰外科

详细信息

中图分类号: R735.8
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出版历程
- 出版日期: 2020-08-20

Role of microRNAs in gallbladder carcinoma

Graduate school of Shanxi Medical University

摘要

摘要:
microRNA(miRNA)是一类广泛存在于真核生物体内的内源性非编码小分子RNA,成熟的miRNA由20～25个核苷酸序列组成。近些年随着研究者对miRNA研究的不断深入,发现其在胆囊癌的发生、发展、预后、化疗耐药以及早期诊断中具有重要作用。对miRNA在胆囊癌中作用的研究进展进行了综述。
- 胆囊肿瘤 /
- 微RNAs /
- 诊断 /
- 治疗学
Abstract:
MicroRNAs(miRNAs) are endogenous non-coding small molecular RNAs that widely exist in eukaryotes,and mature miRNAs are composed of 20-25 nucleotide sequences.With the deepening of the research on miRNAs in recent years,it has been found that miRNAs play an important role in the development,progression,prognosis,chemotherapy resistance,and early diagnosis of gallbladder carcinoma.This article reviews the research advances in the role of miRNAs in gallbladder carcinoma.
- gallbladder neoplasms /
- microRNAs /
- diagnosis /
- therapeutics

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参考文献(43)

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