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非妊娠中年妇女急性戊型肝炎所致死亡1例报告

徐晓桐 金晶兰

引用本文:
Citation:

非妊娠中年妇女急性戊型肝炎所致死亡1例报告

DOI: 10.3969/j.issn.1001-5256.2021.04.036
基金项目: 

吉林省科技厅国际合作项目 (20190701053GH)

利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:徐晓桐负责收集数据,资料分析,撰写论文;金晶兰负责拟定写作思路,指导撰写文章并最后定稿。
详细信息
    作者简介:

    徐晓桐(1995—),女,主要从事肝脏疾病诊治的研究

    通信作者:

    金晶兰,jinjl@jlu.edu.cn

  • 中图分类号: R575.1

Death from acute hepatitis E in a non-pregnant middle-aged woman: A case report

  • 表  1  患者住院期间肝功能及凝血变化

    日期 肝功能 凝血常规
    AST (U/L) ALT (U/L) GGT (U/L) ALP (U/L) Alb (g/L) CHE (U/L) TBil (μmol/L) DBil (μmol/L) APPT (s) PT (s) INR (%) PTA (%)
    2020年7月25日 1961.8 662.2 156.8 210.6 34.0 4958 314.2 254.0 30.5 14.9 1.38 57
    2020年7月29日 2098.6 453.0 105.9 199.4 30.5 4195 388.5 305.3 33.3 17.4 1.58 47
    2020年7月31日 1927.0 319.0 75.3 140.7 29.8 4049 413.4 283.1 35.9 18.4 1.64 45
    2020年8月2日 1047.4 165.6 62.6 137.2 28.7 3389 368.6 262.0 38.0 18.9 1.75 42
    2020年8月5日 1435.6 181.5 66.3 177.2 29.1 2952 476.8 36.8 48.3 31.3 3.04 22
    2020年8月8日 544.3 94.3 40.2 131.2 28.5 2465 490.4 302.9 69.3 46.3 4.45 16
    2020年8月10日 338.5 73.6 59.3 199.0 3.2 2870 497.0 319.6 64.4 39.0 3.70 19
    2020年8月11日 270.2 63.1 53.1 205.2 31.6 2976 493.0 301.3 70.2 49.7 5.10 14
    2020年8月12日 133.1 31.1 3.4 123.9 29.9 4611 363.0 131.3 75.0 150.0
    下载: 导出CSV
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    [6] European Association for the Study of the Liver. EASL Clinical Practice Guidelines on hepatitis E virus infection[J]. J Hepatol, 2018, 68(6): 1256-1271. DOI: 10.1016/j.jhep.2018.03.005.
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    铁涛. 发热为首发症状的戊型病毒性肝炎1例[J]. 实用医药杂志, 2011, 28(11): 1026. DOI: 10.3969/j.issn.1671-4008.2011.11.048.
    [8] GAO PB, ZHAO XY, QIN H, et al. Risk factors for poor prognosis of patients with hepatitis E-induced liver failure[J]. J Prac Hepatol, 2019, 22(2): 220-223. DOI: 10.3969/j.issn.1672-5069.2019.02.017.

    高朋彬, 赵晓彦, 秦浩, 等. 戊型肝炎肝衰竭死亡原因分析[J]. 实用肝脏病杂志, 2019, 22(2): 220-223. DOI: 10.3969/j.issn.1672-5069.2019.02.017.
    [9] ZHAN YH. A case report of shingles with liver damanges as the first manifestation[J]. ShangDong Med, 2009, 49(46): 67. DOI: 10.3969/j.issn.1002-266X.2009.46.083.

    绽永华. 以肝脏损害为首发表现的带状疱疹1例报告[J]. 山东医药, 2009, 49(46): 67. DOI: 10.3969/j.issn.1002-266X.2009.46.083.
    [10] van EIJK J, DALTON HR, RIPELLINO P, et al. Clinical phenotype and outcome of hepatitis E virus-associated neuralgic amyotrophy[J]. Neurology, 2017, 89(9): 909-917. DOI: 10.1212/WNL.0000000000004297.
    [11] THODOU V, BUECHTER M, MANKA P, et al. Course of hepatitis E infection in a patient with rheumatoid arthritis and autoimmune hepatitis: A case report[J]. Medicine (Baltimore), 2017, 96(51): e9407. DOI: 10.1097/MD.0000000000009407.
    [12] LU JX, QIAN SY. Detection of serum anti-mitochondrial antibdies in 56 patients with viral hepatitis E and its clinical significance[J]. Chin J Pract Intern Med, 2003, 23(3): 170-171. DOI: 10.3969/j.issn.1005-2194.2003.03.016.

    卢建溪, 钱师宇. 戊型病毒性肝炎患者56例血清抗线粒体抗体的检测及其临床意义[J]. 中国实用内科杂志, 2003, 23(3): 170-171. DOI: 10.3969/j.issn.1005-2194.2003.03.016.
    [13] TERZIROLI BERETTA-PICCOLI B, RIPELLINO P, GOBBI C, et al. Autoimmune liver disease serology in acute hepatitis E virus infection[J]. J Autoimmun, 2018, 94: 1-6. DOI: 10.1016/j.jaut.2018.07.006.
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    [16] RAWLA P, RAJ JP, KANNEMKUZHIYIL AJ, et al. A systematic review of the extra-hepatic manifestations of hepatitis E virus infection[J]. Med Sci (Basel), 2020, 8(1): 9. DOI: 10.3390/medsci8010009.
    [17] LLOVET LP, GRATACÓS-GINÉS J, ORTIZ O, et al. Higher seroprevalence of hepatitis E virus in autoimmune hepatitis: Role of false-positive antibodies[J]. Liver Int, 2020, 40(3): 558-564. DOI: 10.1111/liv.14332.
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出版历程
  • 收稿日期:  2020-09-29
  • 录用日期:  2020-10-23
  • 出版日期:  2021-04-20
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