原发性胆汁性胆管炎相关瘙痒症的管理
DOI: 10.3969/j.issn.1001-5256.2021.04.049
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:胡凯丽负责资料准备、收集与分析以及论文的撰写;肖丽负责修改论文。
Management of pruritus in primary biliary cholangitis
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摘要: 原发性胆汁性胆管炎(PBC)是一种进行性肝内胆汁淤积性自身免疫性疾病,瘙痒可见于60%~70%的PBC患者,并严重影响患者的生活质量。改善PBC患者的瘙痒症状对提高患者的生活质量有着重要意义。主要总结了PBC的发病机制、PBC相关瘙痒症的治疗进展。Abstract: Primary biliary cholangitis (PBC) is a progressive intrahepatic cholestatic autoimmune disease, and pruritus can be seen in 60%-70% of PBC patients and seriously affects patients' quality of life. Improving the symptoms of pruritus in PBC patients is of great significance for improving their quality of life. This article mainly summarizes the advances in the pathogenesis of PBC and the treatment of PBC-related pruritus.
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Key words:
- Liver Cirrhosis, Biliary /
- Cholestasis /
- Pruritus
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