无合并症的真实慢性乙型肝炎免疫耐受期患者不建议抗病毒治疗

全敏; 邢卉春

doi:10.3969/j.issn.1001-5256.2021.06.011

无合并症的真实慢性乙型肝炎免疫耐受期患者不建议抗病毒治疗

DOI: 10.3969/j.issn.1001-5256.2021.06.011

全敏,
邢卉春^,

首都医科大学附属北京地坛医院肝病三科，北京 100015

基金项目:

北京市医院管理中心扬帆计划 (xmlx201837);

十三五艾滋病和病毒性肝炎等重大传染病防治 (2018ZX10302206－003-006);

北京市医院管理中心消化内科学科协同发展中心项目 (XXT26);

首都卫生发展科研专项 (首发2020-1-2171)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：全敏、邢卉春负责构思和文献检索; 全敏负责起草全文和修改; 邢卉春负责文章修改和审校。

详细信息

通信作者:
邢卉春，hchxing@sohu.com

中图分类号: R512.62
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出版历程
- 收稿日期: 2021-03-23
- 录用日期: 2021-05-15
- 出版日期: 2021-06-20

Antiviral therapy is not recommended in immune-tolerant phase chronic hepatitis B patients without complications

Min QUAN,
Huichun XING^,

Third Department of Liver Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China

摘要

- 乙型肝炎病毒 /
- 乙型肝炎, 慢性 /
- 免疫耐受 /
- 治疗学
- Hepatitis B Virus /
- Hepatitis B, Chronic /
- Immune Tolerance /
- Therapeutics

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参考文献(12)

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[2]	ATTAR BM. CON: All patients with immune-tolerated hepatitis B virus do not need to be treated[J]. Clin Liver Dis (Hoboken), 2020, 15(1): 25-30. DOI: 10.1002/cld.893.
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[9]	KIM GA, LIM YS, HAN S, et al. High risk of hepatocellular carcinoma and death in patients with immune-tolerant-phase chronic hepatitis B[J]. Gut, 2018, 67(5): 945-952. DOI: 10.1136/gutjnl-2017-314904.
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[11]	LIAW YF, BRUNETTO MR, HADZIYANNIS S. The natural history of chronic HBV infection and geographical differences[J]. Antivir Ther, 2010, 15(Suppl 3): 25-33. DOI: 10.3851/IMP1621.
[12]	ANDREANI T, SERFATY L, MOHAND D, et al. Chronic hepatitis B virus carriers in the immunotolerant phase of infection: histologic findings and outcome[J]. Clin Gastroenterol Hepatol, 2007, 5(5): 636-641. DOI: 10.1016/j.cgh.2007.01.005.