肝细胞癌的靶向治疗

张宁宁; 陆伟

doi:10.3969/j.issn.1001-5256.2021.08.003

肝细胞癌的靶向治疗

DOI: 10.3969/j.issn.1001-5256.2021.08.003

张宁宁,
陆伟^,

天津医科大学肿瘤医院肝癌防治研究中心，天津 300060

基金项目:

天津市科技厅项目 (19YFZCSY00020)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：张宁宁负责收集数据，资料分析，撰写论文；陆伟负责课题设计，拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
陆伟，mail4luwei@163.com

中图分类号: R735.7
计量
- 文章访问数: 934
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- 被引次数: 0
出版历程
- 收稿日期: 2021-03-15
- 录用日期: 2021-04-15
- 出版日期: 2021-08-20

Targeted therapy for hepatocellular carcinoma

Ningning ZHANG,
Wei LU^,

Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China

Research funding:

Project of Tianjin Municipal Bureau of Science and Technology (19YFZCSY00020)

摘要

摘要: 近年来，随着肝细胞癌(HCC)分子机制研究深入，靶向治疗也得到了迅猛发展，在延缓和改善患者疾病进展和预后方面作出了巨大贡献。由于HCC的发病机制错综复杂，单一的分子靶向治疗总体临床收益并不理想。因此，近年来靶向联合其他治疗方式的新方案不断出新，并取得了令人鼓舞的成果。就HCC分子靶向治疗药物、研究现状及临床联合应用治疗进展予以简要总结。
- 癌, 肝细胞 /
- 分子靶向治疗
Abstract: With the in-depth research on the molecular mechanism of hepatocellular carcinoma (HCC) in recent years, targeted therapy has achieved rapid development and made great contributions to delaying disease progression and improving prognosis. Due to the complex pathogenesis of HCC, molecular targeted therapy alone has unsatisfactory overall clinical benefits; therefore, new treatment regimens of targeted therapy in combination with other treatment modalities continue to appear in recent years and have obtained encouraging results. This article briefly summarizes the drugs used in molecular targeted therapy, the current research status of molecular targeted therapy, and the advances in its combination with other treatment modalities for HCC.
- Carcinoma, Hepatocellular /
- Molecular Targeted Therapy

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