肝内胆管细胞癌淋巴结转移的预测和治疗
DOI: 10.3969/j.issn.1001-5256.2021.08.040
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:贺康丽、李星悦负责收集文献,归纳分析,撰写论文;贺康丽、刘宏、李星悦负责修改论文;贺康丽、刘宏负责课题设计,拟定写作思路,指导撰写文章并最后定稿。
Prediction and treatment of lymph node metastasis of intrahepatic cholangiocarcinoma
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摘要: 肝内胆管细胞癌(ICC)是第二大原发性肝癌,极易发生淋巴结转移。淋巴结转移的发生不仅影响患者的预后,还决定患者治疗方案的选择。归纳并总结近年国内外ICC的相关文献,阐述了预测ICC淋巴结转移的血清学指标及影像学指标;可接受根治性手术切除患者的在选择淋巴结切除术及术后辅助治疗方面存在的争议;不可手术的晚期ICC患者接受新辅助治疗的研究进展。以期为ICC患者的治疗及淋巴结转移的预测作好理论支持。Abstract: Intrahepatic cholangiocarcinoma (ICC) is the second largest primary liver cancer, and lymph node metastasis of ICC is commonly observed. Lymph node metastasis not only affects the prognosis of patients, but also determines the choice of treatment regimen. This article summarizes related articles on ICC in China and globally and elaborates on the serological markers and imaging indicators for predicting lymph node metastasis of ICC, the controversy over the selection of lymph node resection and postoperative adjuvant treatment for patients eligible for radical resection, and the research advances in neoadjuvant therapy for patients with advanced ICC who cannot undergo surgery, so as to provide theoretical support for the treatment of ICC patients and the prediction of lymph node metastasis.
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Key words:
- Cholangiocarcinoma /
- Lymph Node Metastasis /
- Therapeutics
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