原发性脾血管肉瘤1例报告

王慧君; 牛剑祥; 徐晓艳; 郑卫华; 李朋飞; 刘一博; 张俊晶

doi:10.3969/j.issn.1001-5256.2021.11.036

原发性脾血管肉瘤1例报告

DOI: 10.3969/j.issn.1001-5256.2021.11.036

1.
内蒙古医科大学附属医院肝胆胰脾外科，呼和浩特 010050
2.
内蒙古医科大学病理学教研室，呼和浩特 010030
3.
呼和浩特市第一医院肝胆胰脾外科，呼和浩特 010030

基金项目:

内蒙古自治区草原英才培养专项基金资助项目 (CYYC2012040)

详细信息

通信作者:
张俊晶，zhang.jj@vip.163.com

中图分类号: R733.2
计量
- 文章访问数: 362
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- 被引次数: 0
出版历程
- 收稿日期: 2021-03-30
- 录用日期: 2021-05-06
- 出版日期: 2021-11-20

A case of primary splenic angiosarcoma

1.
Department of Hepatobiliary, Pancreatic, and Splenic Surgery, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
2.
Department of Pathology, Inner Mongolia Medical University, Hohhot 010030, China
3.
Department of Hepatobiliary, Pancreatic, and Splenic Surgery, Hohhot First Hospital, Hohhot 010030, China

Research funding:

Inner Mongolia Autonomous Region Grassland Talent Cultivation Special Fund Project (CYYC2012040)

摘要

- 脾肿瘤 /
- 血管肉瘤 /
- 治疗学
- Splenic Neoplasms /
- Hemangiosarcoma /
- Therapeutics

HTML全文

图 1 术前全腹增强CT检查结果

注：门静脉期见肝脾内弥漫分布小结节状低强化影，周围见液体密度影。

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图 2 骨髓穿刺病理学检查结果

注：a，HE染色(×400)；b，骨髓见梭形细胞，稍有异型，可见血管腔隙，CD34(+)(免疫组化，×400)。

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图 3 术中腔镜视野

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图 4 术后病理学检查结果

注：a，脾内未见皮质、髓质结构，可见残存脾小梁(蓝色箭头)，视野中见大量增生的肿瘤细胞，多排列为裂隙样，部分见坏死(红色箭头) (HE染色，×100)；b，分化较好部位，肿瘤细胞有一定异型性，部分呈鞋钉样，可见血管腔隙(HE染色，×400)；c：分化较差部位肿瘤细胞呈梭形，有一定异型性，呈束状、片状排列，可见裂隙，其内可见一脾小动脉(红色箭头)(HE染色，×400)；d：Ki-67热点区域(15%+)(免疫组化，×400)；e：肿瘤细胞弥漫CD31(+)(免疫组化，×400)；f：肿瘤细胞弥漫FLi1 (+)(免疫组化，×400)。

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参考文献(24)

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