肝硬化肌少症的发病机制与诊疗现状
DOI: 10.3969/j.issn.1001-5256.2022.01.033
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:刘钰懿、陈东风负责调研整理文献,设计论文框架,撰写论文; 颜綦先负责终审论文。
Current status of the pathogenesis, diagnosis, and treatment of sarcopenia in patients with liver cirrhosis
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摘要: 肌少症是肝硬化患者常见的并发症,发病率高达40%~70%,增加肝硬化患者并发症的发生,严重影响患者的生活质量和生存期。肝硬化肌少症发病机制复杂,临床表现易被忽略,诊断标准尚未达成共识,针对性治疗药物较少,亟待临床医生高度重视,并加强其发病机制的研究和治疗药物的研发。Abstract: Sarcopenia is a common complication in patients with liver cirrhosis, with an incidence rate of up to 40%-70%, which increases the incidence rate of complications in patients with liver cirrhosis and seriously affects patients' quality of life and survival time. Sarcopenia in liver cirrhosis has a complex pathogenesis, and its clinical manifestations are easily ignored. No consensus has been reached on diagnostic criteria, and there are few targeted therapeutic drugs. Therefore, it should be taken seriously by clinician and the research on pathogenesis and therapeutic drugs should be strengthened.
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Key words:
- Liver Cirrhosis /
- Sarcopenia /
- Therapeutics
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