宫颈鳞癌胰腺转移致梗阻性黄疸1例报告

叶浩; 易晓雷; 李旭辉; 汪杰; 张军; 刘志鹏; 鲁柱

doi:10.3969/j.issn.1001-5256.2022.03.031

宫颈鳞癌胰腺转移致梗阻性黄疸1例报告

DOI: 10.3969/j.issn.1001-5256.2022.03.031

湖南中医药大学附属长沙市中医医院(长沙市第八医院) 肝胆胰外科，长沙 410100

基金项目:

湖南省卫计委课题项目 (B20180799)

伦理学声明：本例报告已获得患者知情同意。

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：叶浩负责病例资料分析，撰写文章；易晓雷负责拟定写作思路，指导撰写文章并最后定稿；李旭辉、汪杰参与收集数据，修改文章；张军负责对病例特点分析总结；刘志鹏、鲁柱负责收集病例随访资料。

详细信息

通信作者:
易晓雷，yixl70@163.com

计量
- 文章访问数: 526
- HTML全文浏览量: 174
- PDF下载量: 39
- 被引次数: 0
出版历程
- 收稿日期: 2021-07-09
- 录用日期: 2021-08-11
- 出版日期: 2022-03-20

Obstructive jaundice due to pancreatic metastasis from cervical squamous cell carcinoma: A case report

Department of Hepatopancreatobiliary Surgery, Changsha Traditional Chinese Medicine Hospital (Changsha Eighth Hospital) Affiliated to Hunan University of Chinese Medicine, Changsha 410100, China

Research funding:

Hunan Provincial Health and Family Planning Commission Project (B20180799)

More Information

Corresponding author: YI Xiaolei, yixl70@163.com(ORCID:0000-0002-1405-8399)

摘要

- 宫颈肿瘤 /
- 胰腺肿瘤 /
- 肿瘤转移 /
- 黄疸, 阻塞性
- Uterine Cervical Neoplasms /
- Pancreatic Neoplasms /
- Neoplasm Metastasis /
- Jaundice, Obstructive

HTML全文

图 1 全腹盆腔增强CT检查结果

注：a，肝胆管明显扩张，胰管显影；b，动脉期，可见胰头钩突区低密度肿块，胆囊肿大，胆总管下段狭窄；c，静脉期，肿块轻度强化。

下载: 全尺寸图片幻灯片

图 2 术后病理学检查结果

注：a，低倍镜下见癌细胞成团块状或条索状不规则排列(HE染色，×100)；b，高倍镜下见脉管侵犯(HE染色，×400)；c，P16弥漫性阳性表达(免疫组化SP法，×400)；d，P40表达阳性(免疫组化SP法，×400)。

下载: 全尺寸图片幻灯片

参考文献(17)

[1]	WONG B, DICKIE G, GARCIA P, et al. 124I-PET/CT-guided diagnosis and personalized treatment of metastatic papillary thyroid cancer to the pancreas[J]. Clin Nucl Med, 2021, 46(4): 337-339. DOI: 10.1097/RLU.0000000000003499.
[2]	MALEK B, SAIDA S, OLFA J, et al. The management of pancreatic metastasis from synovial sarcoma of the soft tissue: A case report[J]. Rare Tumors, 2020, 12: 2036361320983691. DOI: 10.1177/2036361320983691.
[3]	ADSAY NV, ANDEA A, BASTURK O, et al. Secondary tumors of the pancreas: An analysis of a surgical and autopsy database and review of the literature[J]. Virchows Arch, 2004, 444(6): 527-535. DOI: 10.1007/s00428-004-0987-3.
[4]	LIU AL, FENG YL, ZHAO Y, et al. Pancreatic metastasis from small cell neuroendocrine carcinoma admixed with squamous carcinoma of the uterine cervix: Report of a case and review of literature[J]. Chin J Gastroenterol, 2018, 23(10): 638-639. DOI: 10.3969/j.issn.1008-7125.2018.10.014. 刘爱玲, 冯云路, 赵雨, 等. 宫颈复合型小细胞神经内分泌癌胰腺转移1例并文献复习[J]. 胃肠病学, 2018, 23(10): 638-639. DOI: 10.3969/j.issn.1008-7125.2018.10.014.
[5]	MORI Y, KIDA Y, MATSUSHITA Y, et al. Neuroendocrine carcinoma of uterine cervix: Stereotactic radiotherapy for brain metastasis and stereotactic body radiotherapy for renal and pancreatic metastases[J]. Cureus, 2020, 12(6): e8869. DOI: 10.7759/cureus.8869.
[6]	KIM DJ, PARK JM, KIM JH, et al. Pancreatic metastasis from adenocarcinoma of the uterine cervix[J]. Korean J Gastroenterol, 2019, 73(3): 182-185. DOI: 10.4166/kjg.2019.73.3.182.
[7]	MANUEL V, ROCHA E, FORTINI G, et al. Uterine cancer presenting as obstructive jaundice[J]. Int J Womens Health, 2016, 8: 261-263. DOI: 10.2147/IJWH.S108587.
[8]	LE LARGE T, MEIJER LL, PALECKYTE R, et al. Combined expression of plasma thrombospondin-2 and CA19-9 for diagnosis of pancreatic cancer and distal cholangiocarcinoma: A proteome approach[J]. Oncologist, 2020, 25(4): e634, e643. DOI: 10.1634/theoncologist.2019-0680.
[9]	FANG X, BIAN Y, WANG L, et al. Significance and differential diagnosis of pancreatic imaging examination in clinical decision-making[J]. Chin J Dig Surg, 2020, 19(4): 449-454. DOI: 10.3760/cma.j.cn115610-20200409-00241. 方旭, 边云, 王莉, 等. 胰腺影像学检查在临床决策中的意义及鉴别诊断[J]. 中华消化外科杂志, 2020, 19(4): 449-454. DOI: 10.3760/cma.j.cn115610-20200409-00241.
[10]	LAI JH, LIN HH, LIN CC. Factors affecting cytological results of endoscopic ultrasound guided-fine needle aspiration during learning[J]. Diagn Pathol, 2020, 15(1): 17. DOI: 10.1186/s13000-020-00938-8.
[11]	MENG HL, LI SW, SONG YL, et al. Effect of different cytopathological grading standards on the diagnosis of pancreatic cancer by endoscopic ultrasound-guided fine needle aspiration[J]. J Clin Hepatol, 2021, 37(2): 390-395. DOI: 10.3969/j.issn.1001-5256.2021.02.028. 孟海轮, 李素文, 宋育林, 等. 不同细胞病理学分级标准对超声内镜引导下细针穿刺诊断胰腺癌的影响[J]. 临床肝胆病杂志, 2021, 37, (2): 390-395. DOI: 10.3969/j.issn.1001-5256.2021.02.028.
[12]	HE XJ, LIU Y, ZHANG HY, et al. Diagnosis and treatment of metastasized pancreatic tumor: A report of 25 cases[J]. Chin J Clin Oncol, 2010, 37(11): 651-653. DOI: 10.3969/j.issn.1000-8179.2010.11.015. 何晓军, 刘洋, 张洪义, 等. 胰腺转移肿瘤25例诊治分析[J]. 中国肿瘤临床, Chin J Clin Oncol, 2010, 37(11): 651-653. DOI: 10.3969/j.issn.1000-8179.2010.11.015.
[13]	SHIN TJ, SONG C, JEONG CW, et al. Metastatic renal cell carcinoma to the pancreas: Clinical features and treatment outcome[J]. J Surg Oncol, 2021, 123(1): 204-213. DOI: 10.1002/jso.26251.
[14]	BROZZETTI S, BINI S, de LIO N, et al. Surgical-only treatment of pancreatic and extra-pancreatic metastases from renal cell carcinoma-quality of life and survival analysis[J]. BMC Surg, 2020, 20(1): 101. DOI: 10.1186/s12893-020-00757-0.
[15]	REN G, WANG YJ. Advances in radiotherapy for pancreatic cancer from 2019 to 2020[J]. J Clin Hepatol, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048. 任刚, 王颖杰. 2019年-2020年胰腺癌放射治疗新进展[J]. 临床肝胆病杂志, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048.
[16]	ZHANG W, SHI J, WANG Y, et al. Next-generation sequencing-guided molecular-targeted therapy and immunotherapy for biliary tract cancers[J]. Cancer Immunol Immunother, 2021, 70(4): 1001-1014. DOI: 10.1007/s00262-020-02745-y.
[17]	LEONE P, SOLIMANDO AG, FASANO R, et al. The evolving role of immune checkpoint inhibitors in hepatocellular carcinoma treatment[J]. Vaccines (Basel), 2021, 9(5): 532. DOI: 10.3390/vaccines9050532.