新型无创技术在指导自身免疫性肝炎诊疗中的作用

刘怀鄂; 钱建丹; 张驰; 刘艺琪; 李志; 赵鸿; 王贵强

doi:10.3969/j.issn.1001-5256.2022.04.034

新型无创技术在指导自身免疫性肝炎诊疗中的作用

DOI: 10.3969/j.issn.1001-5256.2022.04.034

刘怀鄂^{1, 2},
钱建丹¹,
张驰¹,
刘艺琪¹,
李志¹,
赵鸿^1, , ,,
王贵强^{1, 3, , ,}

1.
北京大学第一医院感染性疾病科，北京 100034
2.
昆明医科大学第一附属医院感染性疾病科，昆明 650032
3.
北京大学国际医院感染性疾病科，北京 100034

基金项目:

云南省高层次卫生人才项目 (H-2017071);

云南省教育厅科学研究基金项目 (2021J0239)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明: 刘怀鄂负责文献检索及文章撰写; 钱建丹、张弛、刘艺琪、李志负责文献的查找与总结; 赵鸿、王贵强负责文章修改及审定。

详细信息

通信作者:
赵鸿，zhaohong_pufh@btmu.edu.cn

王贵强，john131212@sina.com

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- 被引次数: 0
出版历程
- 收稿日期: 2021-07-29
- 出版日期: 2022-04-20

Role of new noninvasive methods in guiding the diagnosis and treatment of autoimmune hepatitis

Huaie LIU^{1, 2},
Jiandan QIAN¹,
Chi ZHANG¹,
Yiqi LIU¹,
Zhi LI¹,
Hong ZHAO^{1
, ,
,},
Guiqiang WANG^{1, 3
, ,
,}

1.
Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China
2.
Department of Infectious Diseases, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China
3.
Department of Infectious Diseases, Peking University International Hospital, Beijing 100034, China

Research funding:

Yunnan Province High-level Health Talent Project (H-2017071);

Yunnan Provincial Department of Education Research Fund (2021J0239)

More Information

Corresponding author: ZHAO Hong, zhaohong_pufh@btmu.edu.cn(ORCID: 0000-0002-8069-9901); WANG Guiqiang, john131212@sina.com(ORCID: 0000-0002-0317-7536)

摘要

摘要: 自身免疫性肝炎(AIH)是由自身免疫反应介导的肝脏炎症性疾病。准确评估肝脏炎症进展程度，筛选需要皮质类固醇治疗的患者，评价治疗效果，在AIH的诊疗过程中具有重要意义。本文介绍了近年来临床和实验研究中发现的多种具有潜在评估AIH进展程度价值的新型无创技术，并简述了各项技术的优缺点。总结了新型的无创技术在指导AIH的皮质类固醇诊疗过程中具有更多优势，但仍需进一步开展临床研究验证。
- 肝炎, 自身免疫性 /
- 诊断 /
- 治疗学
Abstract: Autoimmune hepatitis (AIH) is an inflammatory disease of the liver mediated by autoimmune response, and in the diagnosis and treatment of AIH, it is of great importance to accurately assess the progression of liver inflammation, screen out the patients requiring corticosteroid therapy, and evaluate the therapeutic outcome. This article introduces a variety of new noninvasive techniques which have been discovered by clinical and experimental studies in recent years and have the potential to evaluate the progression of AIH, as well as the advantages and disadvantages of each technique. It is concluded that the new noninvasive techniques have more advantages in guiding the corticosteroid therapy for AIH, but further clinical studies are still needed for verification.
- Hepatitis, Autoimmune /
- Diagnosis /
- Therapeutics

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