微小RNA-200c在胰腺癌中的研究进展

张尧; 张锴; 康鹏东; 马超

doi:10.3969/j.issn.1001-5256.2022.04.045

微小RNA-200c在胰腺癌中的研究进展

DOI: 10.3969/j.issn.1001-5256.2022.04.045

郑州大学附属肿瘤医院肝胆胰外科，郑州 450008

基金项目:

河南省科技厅科技攻关项目 (162102310315)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：张尧负责文献整理，撰写论文；张锴、康鹏东参与查阅文献，修改论文；马超负责拟定写作方向，指导撰写文章并最终定稿。

详细信息

通信作者:
马超，mjc1566@sina.com

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- 被引次数: 0
出版历程
- 收稿日期: 2021-07-31
- 录用日期: 2021-10-26
- 出版日期: 2022-04-20

Research advances in microRNA-200c in pancreatic cancer

Department of Hepatopancreatobiliary Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

Research funding:

Science and Technology Key Project of Henan Province (162102310315)

More Information

Corresponding author: MA Chao, mjc1566@sina.com(ORCID: 0000-0002-6894-1259)

摘要

摘要: 微小RNA-200c(miR-200c)是一类非编码小分子RNA，参与基因转录后水平调控，与肿瘤的发生发展密切相关。本文介绍了miR-200c对胰腺癌侵袭和转移的抑制作用，及其在胰腺癌的早期诊断、预后判断等方面的临床应用价值，提示miR-200c可作为抑癌基因及有效分子标志物和未来临床研究重点。
- 微RNAs /
- 胰腺肿瘤 /
- 诊断 /
- 治疗学
Abstract: MicroRNA-200c (miR-200c) is a type of non-coding small molecule RNA, which is involved in the post-transcriptional regulation of genes and is closely associated with the development and progression of tumor. This article introduces the inhibitory effect of miR-200c on the invasion and metastasis of pancreatic cancer and the clinical application value of miR-200c in the early diagnosis and prognostic evaluation of pancreatic cancer. It is pointed out that miR-200c can be used as a tumor suppressor gene and an effective molecular marker for further clinical research.
- MicroRNAs /
- Pancreatic Neoplasms /
- Diagnosis /
- Therapeutics

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参考文献(41)

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