肝移植治疗慢加急性肝衰竭的临床研究进展

李江; 代星; 田大治; 蒋文涛; 沈中阳

doi:10.3969/j.issn.1001-5256.2022.05.045

肝移植治疗慢加急性肝衰竭的临床研究进展

DOI: 10.3969/j.issn.1001-5256.2022.05.045

李江^1, , ,,
代星²,
田大治¹,
蒋文涛¹,
沈中阳¹

1.
天津市第一中心医院肝移植科，天津 300110
2.
天津医科大学一中心学院，天津 300110

基金项目:

国家自然科学基金面上项目 (82072219);

天津市自然科学基金 (17JCQNJC12800)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：李江负责课题设计，资料分析，撰写论文; 代星、田大治、蒋文涛参与收集数据，修改论文; 沈中阳负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
李江，lijiang_009@163.com

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- 被引次数: 0
出版历程
- 收稿日期: 2021-09-14
- 录用日期: 2021-10-18
- 出版日期: 2022-05-20

Advances in the clinical research on liver transplantation in treatment of acute-on-chronic liver failure

1.
Department of Liver Transplantation, Tianjin First Central Hospital, Tianjin 300110, China
2.
The First Central College of Tianjin Medical University, Tianjin 300110, China

Research funding:

Nation Natural Science Foundation of China (General Program) (82072219);

Natural Science Foundation of Tianjin (17JCQNJC12800)

More Information

Corresponding author: LI Jiang, lijiang_009@163.com(ORCID: 0000-0002-2368-9942)

摘要

摘要: 慢加急性肝衰竭是一种慢性肝脏疾病急性加重导致的肝功能急剧恶化的疾病，其通常会伴随多个器官功能衰竭且预后比普通肝硬化差。许多研究认为慢加急性肝衰竭患者若能及时行肝移植手术可以显著提高生存率，然而目前没有可靠的指南指出患者肝移植手术的适应证。本文归纳了近年相关研究并对慢加急性肝衰竭肝移植的指征、时机、预后进行探讨。
- 慢加急性肝功能衰竭 /
- 肝移植 /
- 肝，人工 /
- 多器官功能衰竭
Abstract: Acute-on-chronic liver failure (ACLF) is a disease of rapid deterioration of liver function caused by the acute exacerbation of chronic liver diseases, and it is often associated with multiple organ failure and has a poorer prognosis than common liver cirrhosis. Many studies suggest that timely liver transplantation can significantly improve the survival rate of patients with ACLF; however, there are currently no reliable guidelines that point out the indications for liver transplantation in patients with ACLF. This article summarizes recent studies and discusses the indication, timing, and prognosis of liver transplantation in ALCF patients.
- Acute-On-Chronic Liver Failure /
- Liver Transplantation /
- Liver, Artificial /
- Multiple Organ Failure

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参考文献(38)

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