纳米载药系统在肝癌治疗中的研究进展
DOI: 10.3969/j.issn.1001-5256.2022.08.037
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:王淼东负责课题设计并撰写论文;陈泽山、彭佩纯参与收集数据,修改论文;邓鑫负责指导撰写论文并最后定稿。
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摘要: 传统手术切除、放疗、化疗在肝癌治疗中占据主导地位。然而,化疗药物的毒副作用、疗效不稳定以及靶点不明确常限制了其在肝癌患者中的应用。因此,为了提高药物在肝癌治疗中的疗效,近些年在生物医学领域发展起来的纳米医学进入了人们的视野。纳米载药系统以低毒、生物利用度广、药物释放可控、稳定性好等优势被逐渐应用于临床研究,本文将着重介绍纳米载药系统在肝癌治疗中的最新进展。Abstract: Traditional surgical resection, radiotherapy, and chemotherapy still play a dominant role in the treatment of liver cancer; however, their application in liver cancer patients is often limited by the toxic and side effects, unstable efficacy, and unclear targets of chemotherapeutic drugs. Therefore, in order to improve the efficacy of drugs in the treatment of liver cancer, nanomedicine, which has been developed in the biomedical field in recent years, has attracted more and more attention. Nano-drug delivery system has been gradually applied in clinical research for its advantages of low toxicity, wide bioavailability, controllable drug release, and good stability. This article focuses on the latest research advances in nano-drug delivery system in the treatment of liver cancer.
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Key words:
- Liver Neoplasms /
- Nano Drug Delivery System /
- Therapeutics
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