系统免疫炎症指数与胰腺癌预后的相关性
DOI: 10.3969/j.issn.1001-5256.2022.11.046
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:周发权、陈师负责文献检索,撰写文章;孙红玉、汤礼军负责指导撰写文章并最后定稿。
Correlation of systemic immune-inflammation index and pancreatic cancer prognosis, recent research progress
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摘要: 炎症广泛参与肿瘤的发生与发展,对胰腺癌进展起着至关重要的作用。同时炎性细胞是构成肿瘤微环境的一部分, 在促进肿瘤细胞的增殖和侵袭性转移起着关键作用。近年来,越来越多的研究探讨以中性粒细胞、淋巴细胞和血小板为基础的系统免疫炎症指数与恶性肿瘤患者预后的关系,其中也包括对胰腺癌的研究。本文通过阐述系统免疫炎症指数与胰腺癌患者预后的关系,为制订适当的胰腺癌治疗策略提供参考。Abstract: Inflammation is associated with cancer development and plays a crucial role in pancreatic cancer progression. Inflammatory cell infiltration in the tumor lesion is a part of the tumor microenvironment, which could promote tumor cell proliferation, invasion, and metastasis. Recently developed systemic immune-inflammation index (SII) based on level of neutrophils, lymphocytes, and platelets was used to predict prognosis of cancer patients, including pancreatic cancer patients. This review summarized and discussed recent research progress on correlation of systemic immune-inflammation index and pancreatic cancer prognosis to provide appropriate treatment selections.
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Key words:
- Pancreatic Neoplasms /
- Systemic Immune-Inflammation Index /
- Prognosis
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