巨大胆管内乳头状黏液性肿瘤破裂致慢性胶冻样腹水1例报告

陈聪颖; 张汝玲; 乔良; 陆伦根; 周慧

doi:10.3969/j.issn.1001-5256.2023.01.022

巨大胆管内乳头状黏液性肿瘤破裂致慢性胶冻样腹水1例报告

DOI: 10.3969/j.issn.1001-5256.2023.01.022

上海市第一人民医院消化科，上海 200080

基金项目:

上海市科委项目 (19411951402)

伦理学声明：本例报告已获得患者知情同意。

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：陈聪颖负责课题设计，资料分析，撰写论文；张汝玲、乔良参与收集数据，修改论文；陆伦根、周慧负责拟定思路，指导撰写文章并最后定稿。

详细信息

通信作者:
周慧，mdzhouhui@163.com (ORCID: 0000-0002-2565-8584)

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出版历程
- 收稿日期: 2022-05-22
- 录用日期: 2022-06-27
- 出版日期: 2023-01-20

A case of chronic gelatinous ascites caused by giant intraductal papillary mucinous neoplasm of the bile tract

Department of Gastroenterology, Shanghai General Hospital, Shanghai 200080, China

Research funding:

Project of Shanghai Science & Technology Department (19411951402)

More Information

Corresponding author: ZHOU Hui, mdzhouhui@163.com (ORCID: 0000-0002-2565-8584)

摘要

- 胆管肿瘤 /
- 乳头状瘤 /
- 腹水 /
- 诊断 /
- 治疗学
- Bile Duct Neoplasms /
- Papilloma /
- Ascites /
- Diagnosis /
- Therapeutics

HTML全文

图 1 患者术前增强CT及MRCP检查

注：a，肝左叶巨大囊实性占位；b，肝左叶占位内见分隔，实性成分及分隔可见强化(箭头所指为囊壁强化)；c，左肝内胆管明显扩张，远端见囊实性占位。

Figure 1. Preoperative enhanced CT and MRCP

下载: 全尺寸图片幻灯片

图 2 患者术后病理检查

注：a，术后大体标本，箭头所指见胶冻样黏液；b，肝左叶IPMN伴重度异型增生(HE染色，×100); c, 箭头所指为浸润性成分(HE染色，×100)。

Figure 2. Postoperative pathological examination

下载: 全尺寸图片幻灯片

参考文献(16)

[1]	LI RR, CHEN YY, ZHOU S. A case of intraductal papillary mucinous neoplasm of the bile tract[J/CD]. Chin J Hepatic Surg(Electronic Edition), 2020, 9(6): 609-612. DOI: 10.3877/cma.j.issn.2095-3232.2020.06.023. 李冉冉, 陈永艺, 周松. 胆管内乳头状黏液性肿瘤一例[J/CD]. 中华肝脏外科手术学电子杂志, 2020, 9(6): 609-612. DOI: 10.3877/cma.j.issn.2095-3232.2020.06.023.
[2]	LIAO HJ, XIE AW, YU Y, et al. Intraductal papillary mucinous neoplasm of the bile tract: a single-center clinical study on 21 patients[J]. J Hepatopancreatobiliary Surg, 2020, 32(3): 148-151. DOI: 10.11952/j.issn.1007-1954.2020.03.005. 廖辉军, 谢敖文, 于毅, 等. 胆管内乳头状黏液性肿瘤21例临床分析[J]. 肝胆胰外科杂志, 2020, 32(3): 148-151. DOI: 10.11952/j.issn.1007-1954.2020.03.005.
[3]	XU Y, TANG J, HE QY, et al. Intraductal papillary mucinous neoplasm of the bile tract: a single-center clinical study on 21 patients[J]. J Clin Hepatol, 2021, 37(12): 2981-2985. DOI: 10.3969/j.issn.1001-5256.2021.12.052. 徐颖, 唐加, 何清云, 等. 胆管导管内乳头状黏液性肿瘤的研究现状[J]. 临床肝胆病杂志, 2021, 37(12): 2981-2985. DOI: 10.3969/j.issn.1001-5256.2021.12.052.
[4]	LU BC, YANG JH, TANG HJ, et al. Intraductal papillary mucinous neoplasm: a report of 6 cases and literature review[J]. Chin J Hepatobiliary Surg, 2019, 25(12): 942-944. DOI: 10.3760/cma.j.issn.1007-8118.2019.12.014. 鲁葆春, 杨建辉, 唐海军, 等. 胆管内乳头状黏液性肿瘤六例并文献复习[J]. 中华肝胆外科杂志, 2019, 25(12): 942-944. DOI: 10.3760/cma.j.issn.1007-8118.2019.12.014.
[5]	CHEN JC, CHEN XJ, CHEN L, et al. Intraductal papillary mucinous neoplasm of the bile tract: a report of 3 cases[J]. J Hepatopancreatobiliary Surg, 2017, 29(1): 71-73. DOI: 10.11952/j.issn.1007-1954.2017.01.019. 陈家诚, 陈小菁, 陈良, 等. 胆管内乳头状黏液性肿瘤三例[J]. 肝胆胰外科杂志, 2017, 29(1): 71-73. DOI: 10.11952/j.issn.1007-1954.2017.01.019.
[6]	DING X, WANG LH, JIANG G, et al. Endoscopic retrograde cholangiopancreatography combined with Spyglass in diagnosis of common bile duct papillary myxoma: A case report[J]. J Clin Hepatol, 2021, 37(12): 2902-2904. DOI: 10.3969/j.issn.1001-5256.2021.12.034. 丁玄, 王林恒, 江贵, 等. 内镜逆行胰胆管造影联合SpyGlass诊断胆总管乳头状黏液瘤1例报告[J]. 临床肝胆病杂志, 2021, 37(12): 2902-2904. DOI: 10.3969/j.issn.1001-5256.2021.12.034.
[7]	NAKANUMA Y, UESAKA K, KAKUDA Y, et al. Intraductal papillary neoplasm of bile duct: updated clinicopathological characteristics and molecular and genetic alterations[J]. J Clin Med, 2020, 9(12): 3991. DOI: 10.3390/jcm9123991.
[8]	KUBOTA K, JANG JY, NAKANUMA Y, et al. Clinicopathological characteristics of intraductal papillary neoplasm of the bile duct: a Japan-Korea collaborative study[J]. J Hepatobiliary Pancreat Sci, 2020, 27(9): 581-597. DOI: 10.1002/jhbp.785.
[9]	LI RK, LIN HM, YAN FH, et al. Classification and imaging findings of hepatic cystic lesions[J]. Radiol Prac, 2017, 32(8): 802-807. DOI: 10.13609/j.cnki.1000-0313.2017.08.004. 李若坤, 林慧敏, 严福华, 等. 肝脏囊性病变的分类及影像学表现[J]. 放射学实践, 2017, 32(8): 802-807. DOI: 10.13609/j.cnki.1000-0313.2017.08.004.
[10]	HE MN, ZHANG J, ZHANG Q, et al. Research advances in clinical and imaging characteristics of intraductal papillary mucinous neoplasm of the bile duct[J]. Acta Academiae Medicinae Sinicae, 2017, 39(3): 451-455. DOI: 10.3881/j.issn.1000-503X.2017.03.026. 何蒙娜, 张璟, 张青, 等. 胆管内乳头状黏液性肿瘤的临床表现与影像学特征研究进展[J]. 中国医学科学院学报, 2017, 39(3): 451-455. DOI: 10.3881/j.issn.1000-503X.2017.03.026.
[11]	RAMZI J, FERETIS M, HICKMAN KE, et al. Preoperative diagnosis of intraductal papillary neoplasm of the bile duct with endoscopic ultrasound[J]. Ann R Coll Surg Engl, 2021, 103(2): e65-e68. DOI: 10.1308/rcsann.2020.7010.
[12]	LOU JY, SU W, WEI SM, et al. Clinical features, diagnosis and treatment of intraductal papillary neoplasm of the bile duct[J]. Chin J Surg, 2018, 56(5): 350-354. DOI: 10.3760/cma.j.issn.0529-5815.2018.05.006. 楼健颖, 粟伟, 魏树梅, 等. 胆管导管内乳头状肿瘤的临床特征及诊治分析[J]. 中华外科杂志, 2018, 56(5): 350-354. DOI: 10.3760/cma.j.issn.0529-5815.2018.05.006.
[13]	WANG X, CAI YQ, CHEN YH, et al. Biliary tract intraductal papillary mucinous neoplasm: report of 19 cases[J]. World J Gastroenterol, 2015, 21(14): 4261-4267. DOI: 10.3748/wjg.v21.i14.4261.
[14]	MO A, BRAT G, SPOLVERATO G, et al. Intraductal papillary mucinous neoplasm of the liver: GI image[J]. J Gastrointest Surg, 2015, 19(4): 792-794. DOI: 10.1007/s11605-015-2750-2.
[15]	CHENG CD, KONG R, SUN B. Progress in diagnosis and treatment of intraductal papillary mucinous neoplasm of the bile tract[J]. Chin J Prac Surg, 2017, 37(8): 929-931. DOI: 10.19538/j.cjps.issn1005-2208.2017.08.26. 程春东, 孔瑞, 孙备. 胆管内乳头状黏液性肿瘤诊治进展[J]. 中国实用外科杂志, 2017, 37(8): 929-931. DOI: 10.19538/j.cjps.issn1005-2208.2017.08.26.
[16]	XIN Q, ZHAO PC, YU XY, et al. Clinical characteristics and prognosis of intraductal papillary mucinous neoplasm of the biliary tract[J]. Chin J Oncol, 2020, 42(10): 891-896. DOI: 10.3760/cma.j.cn112152-20190806-00502. 辛奇, 赵鹏程, 于小源, 等. 胆管导管内乳头状黏液性肿瘤的临床病理特征和预后[J]. 中华肿瘤杂志, 2020, 42(10): 891-896. DOI: 10.3760/cma.j.cn112152-20190806-00502.