自身免疫性肝炎的药物治疗进展
DOI: 10.3969/j.issn.1001-5256.2023.04.026
利益冲突声明:所有作者均声明不存在利益冲突。
作者贡献声明:杨秀英负责查找文献,分析资料,文章撰写;党小红和姜洋负责文章修改和定稿。
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摘要: 自身免疫性肝炎是一种免疫介导的慢性炎症性肝病,目前标准治疗对大多数患者有效,对标准治疗应答不佳或不能耐受药物副作用的患者可以选择二线或三线药物治疗。随着对发病机制的深入探索,新型的治疗方法正在试验中。本文对目前自身免疫性肝炎的药物治疗研究进展作一综述。Abstract: Autoimmune hepatitis (AIH) is an immune-mediated chronic inflammatory liver disease. At present, standard treatment is effective in most AIH patients, and second- or third-line pharmacotherapy can be selected for patients who have suboptimal response to standard treatment or cannot tolerate the side-effects of the drugs. Novel therapies are undergoing clinical trials with the further exploration of the pathogenesis of AIH. This article reviews the current research advances in pharmacotherapy for AIH.
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Key words:
- Hepatitis, Autoimmune /
- Drug Therapy /
- Therapeutics
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