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脾脏硬度预测肝硬化患者门静脉高压及其并发症的研究现状
DOI: 10.3969/j.issn.1001-5256.2023.05.029
利益冲突声明：本文不存在任何利益冲突。
作者贡献声明：刘积庆负责相关文献资料的收集和分析，论文初稿的写作；孟繁坤、丁惠国、李建军、黄群参与收集数据及修改论文；张晶、祖红梅负责拟定写作思路，指导撰写文章并最后定稿。
Current research status of spleen stiffness measurement in predicting portal hypertension and its complications in patients with liver cirrhosis
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摘要: 肝脏硬度测量在临床上已经广泛应用于门静脉高压的预测。近年来，脾脏硬度测量(SSM)成为一种诊断工具，研究证明其可以预测慢性肝病患者门静脉高压及食管胃静脉曲张出血等并发症，辅助进行门静脉高压和食管胃静脉曲张出血风险分层管理；能够准确预测慢性肝病患者的临床显著性门静脉高压、高危食管胃静脉曲张、失代偿率和病死率。目前大部分研究中SSM数据都来自于使用肝脏设备FibroScanⓇ(SSM@50 Hz)检测。FibroScanⓇ 630是新的脾脏专用硬度扫描仪，拥有专用的脾脏硬度测量模式(SSM@100 Hz)。本文将介绍目前脾脏硬度用于预测门静脉高压的意义，并简要介绍新的脾脏硬度检测设备的优缺点。Abstract: Liver stiffness measurement (LSM) has been widely used in predicting portal hypertension in clinical practice, and in recent years, spleen stiffness measurement (SSM) has also become a diagnostic tool. Studies have shown that SSM can predict portal hypertension and its complications such as esophagogastric variceal bleeding in patients with chronic liver diseases and assist in the risk stratification management of portal hypertension and esophagogastric variceal bleeding. It can accurately predict clinically significant portal hypertension, high-risk esophageal and gastric varices, decompensation rate, and mortality rate in patients with chronic liver diseases. At present, SSM data in most studies are obtained by detection using the liver equipment FibroScanⓇ (SSM@50 Hz). FibroScanⓇ 630 is a new scanner dedicated for SSM with a special mode for SSM (SSM@100 Hz). This article elaborates on the significance of SSM in predicting portal hypertension and briefly introduces the advantages and disadvantages of the new equipment for SSM.
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