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多学科联合诊疗原发性肝脏神经内分泌瘤1例报告

赵凯越 严哲 黄缘

引用本文:
Citation:

多学科联合诊疗原发性肝脏神经内分泌瘤1例报告

DOI: 10.3969/j.issn.1001-5256.2023.06.024
伦理学声明:本例报告已获得患者知情同意。
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:赵凯越负责资料分析,撰写论文,修改论文;严哲负责收集资料、患者随访;黄缘负责拟定写作思路,指导撰写文章及审阅。
详细信息
    通信作者:

    HUANG Yuan, huangy9815@163.com(ORCID: 0000-0003-1392-4619)

Multidisciplinary diagnosis and treatment of primary hepatic neuroendocrine tumor

  • 图  1  肝胆胰脾超声检查

    注:第二肝门处可见一低回声肿物,大小约8.7 cm×5.6 cm,边界清,累及右肝前叶及左肝内叶,周围为肝静脉、门静脉右支及下腔静脉。

    Figure  1.  Ultrasound examination of liver, bile, pancreas and spleen

    图  2  全腹增强CT

    注:a,肝脏S4/8/1扫及巨大混杂密度强化灶,动脉期明显强化,肝左及中静脉受累,肝总管、右侧肝内胆管轻度扩张,病灶最大截面61 mm×102 mm,病灶边缘见囊性水样密度灶,与主体肿块分界不清;b,肿物呈“快进快出”强化方式;c,肿物呈“快进快出”强化方式。

    Figure  2.  Whole abdomen enhanced CT

    图  3  术前三维影像评估

    注:肝脏体积2 236.7 cm3,结节总体积331.74 cm3,剩余肝脏体积1 905.01 cm3,总结节/肝脏体积比14.83%,肝内除血管和结节体积1 895.11 cm3

    Figure  3.  Preoperative 3D imaging assessment

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    吴文铭, 陈洁, 白春梅, 等. 中国胰腺神经内分泌肿瘤诊疗指南(2020)[J]. 协和医学杂志, 2021, 12(4): 460-480. DOI: 10.12290/xhyxzz.2021-0481.
    [2] SONG JE, KIM BS, LEE CH. Primary hepatic neuroendocrine tumor: A case report and literature review[J]. World J Clin Cases, 2016, 4(8): 243-247. DOI: 10.12998/wjcc.v4.i8.243.
    [3] MENG XF, PAN YW, WANG ZB, et al. Primary hepatic neuroendocrine tumor case with a preoperative course of 26 years: A case report and literature review[J]. World J Gastroenterol, 2018, 24(24): 2640-2646. DOI: 10.3748/wjg.v24.i24.2640.
    [4] EDMONDSON HA. Tumors of the liver and intrahepatic bile ducts[M]. Washington: Armed Fores Institute of Pathology, 1958: 105-109.
    [5] BASUROY R, BOUVIER C, RAMAGE JK, et al. Delays and routes to diagnosis of neuroendocrine tumours[J]. BMC Cancer, 2018, 18(1): 1122. DOI: 10.1186/s12885-018-5057-3.
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    [7] LV Y, HUANG C, XU H, et al. Clinicopathological characteristics of the primary and metastatic hepatic neuroendocrine tumors and the relevant prognosis-related factors: A retrospective study of 81 cases in a single Chinese center[J]. J Cancer, 2018, 9(3): 479-487. DOI: 10.7150/jca.22157.
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    郑琴芳, 何志钧, 农兵. 原发性肝脏神经内分泌肿瘤诊断的研究进展[J]. 胃肠病学, 2018, 23(8): 506-508. DOI: 10.3969/j.issn.1008-7125.2018.08.013.
    [9] Chinese Society of Clinical Oncology Guidelines Working Committee. The Chinese Society of Clinical Oncology (CSCO): Clinical Guildlines for the Diagnosis and Treatment of Neuroendocrine Neoplasms, 2021[M]. Beijing: People's Medical Publishing House, 2021: 51.

    中国临床肿瘤学会指南工作委员会. CSCO神经内分泌肿瘤诊疗指南2021[M]. 北京: 人民卫生出版社, 2021: 51.
    [10] SONG S, KOH Y. Primary hepatic neuroendocrine tumor arising at a young age: Rare case report and literature review[J]. Korean J Gastroenterol, 2022, 79(1): 35-40. DOI: 10.4166/kjg.2021.139.
    [11] ZHAO S, CHENG C, ZUO CJ. The clinical value of combined 68Ga-SSA/18F-FDG PET/CT imaging in neuroendocrine neoplasms[J]. Chin J Nucl Med Mol Imaging, 2020, 40(1): 47-51. DOI: 10.3760/cma.j.issn.2095-2848.2020.01.012.

    赵帅, 程超, 左长京. 68Ga-SSA/18F-FDG PET/CT联合显像在神经内分泌肿瘤诊治中的应用价值[J]. 中华核医学与分子影像杂志, 2020, 40(1): 47-51. DOI: 10.3760/cma.j.issn.2095-2848.2020.01.012.
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  • 收稿日期:  2022-11-21
  • 录用日期:  2022-12-25
  • 出版日期:  2023-06-20
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