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骨髓增生性疾病所致门静脉海绵样变性1例报告

韩冰 涂传涛

引用本文:
Citation:

骨髓增生性疾病所致门静脉海绵样变性1例报告

DOI: 10.3969/j.issn.1001-5256.2023.06.025
基金项目: 

国家自然科学基金 (81970531);

上海市虹口区卫生健康委员会面上项目 (2002-16)

伦理学声明:本例报告已获得患者/患者家属知情同意。
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:韩冰负责课题设计,资料分析,撰写论文;涂传涛负责拟定写作思路,收集资料,指导撰写文章并最后定稿。
详细信息
    通信作者:

    TU Chuantao, tuchuantao@hotmail.com(ORCID: 0000-0002-9106-9868)

Cavernous transformation of the portal vein caused by myeloproliferative disease: A case report

Research funding: 

National Natural Science Foundation of China (81970531);

General Project of Shanghai Hongkou District Health Commission (2002-16)

  • 图  1  胃镜结果

    注:a,食管数条纵行静脉曲张充盈;b,胃底静脉曲张球伴表面糜烂。

    Figure  1.  Gastroscopic results

    图  2  门静脉增强CT结果

    注:a,门静脉海绵样变性;b,腹腔多发分支血管扭曲,脾肿大。

    Figure  2.  Portal vein enhanced CT results

    图  3  骨髓穿刺Wright-Giemsa染色结果

    注:a,骨髓增生活跃,巨核系多见,部分胞浆丰富,体积巨大(×100);b,巨核细胞胞浆丰富、体积巨大(×400);c,巨核细胞胞浆丰富、体积巨大,可见局部区域血小板形成(×1 000);d,巨核细胞胞浆丰富、体积巨大且核分叶较多(×400);e,巨核细胞胞浆丰富、体积巨大且核分叶较多,可见边缘血小板形成(×1 000)。

    Figure  3.  Bone marrow puncture results

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    [4] ZHANG BJ, HAN GH, FAN DM. Research advances in non-cirrhotic portal hypertension[J]. J Clin Hepatol, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009.

    张博静, 韩国宏, 樊代明. 非肝硬化性门静脉高压症的研究现状[J]. 临床肝胆病杂志, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009.
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    [6] DELEVE LD, VALLA DC, GARCIA-TSAO G, et al. Vascular disorders of the liver[J]. Hepatology, 2009, 49(5): 1729-1764. DOI: 10.1002/hep.22772.
    [7] LI H, SUN PM, SUN HW, et al. Progress in clinical diagnosis and treatment of cavernous transformation of the portal vein[J]. World Chin J Dig, 2021, 29(12): 662-669. DOI: 10.11569/wcjd.v29.i12.662j.

    李昊, 孙培鸣, 孙宏伟, 等. 门静脉海绵样变性的临床诊疗进展[J]. 世界华人消化杂志, 2021, 29(12): 662-669. DOI: 10.11569/wcjd.v29.i12.662j.
    [8] RUNGJIRAJITTRANON T, OWATTANAPANICH W, UNGPRASERT P, et al. A systematic review and meta-analysis of the prevalence of thrombosis and bleeding at diagnosis of Philadelphia-negative myeloproliferative neoplasms[J]. BMC Cancer, 2019, 19(1): 184. DOI: 10.1186/s12885-019-5387-9.
    [9] LEVINE RL, WADLEIGH M, COOLS J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis[J]. Cancer Cell, 2005, 7(4): 387-397. DOI: 10.1016/j.ccr.2005.03.023.
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    [11] SUN CC, LI Y, TIAN WJ, et al. JAK2V617F mutation and TNF-α expression in myeloproliferative neoplasms and their correlation[J]. J Exp Hematol, 2014, 22(4): 1022-1026. DOI: 10.7534/j.issn.1009-2137.2014.04.025.

    孙聪聪, 李英, 田文君, 等. 骨髓增殖性肿瘤中JAK2V617F突变和TNF-α的表达及两者的相关性研究[J]. 中国实验血液学杂志, 2014, 22(4): 1022-1026. DOI: 10.7534/j.issn.1009-2137.2014.04.025.
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出版历程
  • 收稿日期:  2022-10-20
  • 录用日期:  2022-11-27
  • 出版日期:  2023-06-20
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