HIV感染者非酒精性脂肪性肝病的临床研究进展

芦佳骏; 费发珠; 任宾

doi:10.3969/j.issn.1001-5256.2023.06.030

HIV感染者非酒精性脂肪性肝病的临床研究进展

DOI: 10.3969/j.issn.1001-5256.2023.06.030

青海大学附属医院肝胆胰外科, 青海省包虫病研究重点实验室, 西宁 810001

基金项目:

2021年度青海省“昆仑英才·高端创新创业人才”

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：芦佳骏负责课题设计，资料分析，撰写论文；芦佳骏、费发珠参与收集数据，修改论文；任宾负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
任宾, renbing51@aliyun.com (ORCID：0000-0002-9742-4082)

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出版历程
- 收稿日期: 2022-11-20
- 录用日期: 2023-01-02
- 出版日期: 2023-06-20

Research advances in nonalcoholic fatty liver disease in individuals with HIV infection

Qinghai Province Key Laboratory of Hydatid Disease Research, Department of Hepatobiliary and Pancreatic Surgery, The Affiliated Hospital of Qinghai University, Xining 810001, China

Research funding:

2021 Qinghai Province “Kunlun Talents· High － end Innovative and Entrepreneurial Talents”

More Information

Corresponding author: REN Bin, renbing51@aliyun.com (ORCID: 0000-0002-9742-4082)

摘要

摘要:
非酒精性脂肪性肝病(NAFLD)在全球总人口中的患病率呈现逐步增加趋势，由NAFLD导致的肝脏恶性肿瘤的发病率也不断上升。肥胖是NAFLD发生的独立危险因素。在体质量正常的HIV感染者中，25%患有NAFLD，消瘦型NAFLD在HIV感染者中较为常见。本文在查阅国内外文献的基础上，对HIV感染者NAFLD的流行病学、病理生理学、组织学、诊断、筛查、干预措施、治疗及临床管理进行概述，以期提高公众、临床医师及相关管理机构对HIV感染者NAFLD的认识。
- HIV /
- 非酒精性脂肪性肝病 /
- 临床研究
Abstract:
The prevalence rate of nonalcoholic fatty liver disease (NAFLD) tends to increase in the general population around the world, and the incidence rate of liver malignancies caused by NAFLD is also increasing continuously. Obesity is an independent risk factor for NAFLD. Among the individuals with HIV infection who have a normal body weight, 25% have NAFLD, and lean NAFLD is relatively common in individuals with HIV infection. With reference to related articles in China and globally, this article reviews the epidemiology, pathophysiology, histology, diagnosis, screening, intervention, treatment, and clinical management of NAFLD, in order to improve the awareness of NAFLD in individuals with HIV infection among the public, clinicians, and related institutions.
- HIV /
- Non-alcoholic Fatty Liver Disease /
- Clinical Studies

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参考文献(56)

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