肝移植治疗难治性肝炎性肌纤维母细胞瘤1例报告

解鸿跃; 周喆聿; 邵光鑫; 孙玖玖; 徐晓亮; 孙倍成

doi:10.3969/j.issn.1001-5256.2023.07.022

肝移植治疗难治性肝炎性肌纤维母细胞瘤1例报告

DOI: 10.3969/j.issn.1001-5256.2023.07.022

解鸿跃¹,
周喆聿¹,
邵光鑫²,
孙玖玖³,
徐晓亮^2, , ,,
孙倍成^{1, 2, 3}

1.
北京协和医学院南京鼓楼医院肝胆胰中心，南京 210008
2.
南京大学医学院附属鼓楼医院肝胆胰中心，南京 210008
3.
东南大学医学院南京鼓楼医院肝胆胰中心，南京 210008

基金项目:

国家自然科学基金青年项目 (82103135)

伦理学声明：本例报告已获得患者知情同意。

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：解鸿跃、周喆聿负责资料分析，论文撰写；邵光鑫、孙玖玖参与收集数据，修改论文；孙倍成、徐晓亮负责课题设计，指导写作并最后定稿。

详细信息

通信作者:
徐晓亮，xuxiaoliang1990@yeah.net (ORCID：0000-0002-3617-6193)

计量
- 文章访问数: 356
- HTML全文浏览量: 104
- PDF下载量: 48
- 被引次数: 0
出版历程
- 收稿日期: 2022-11-21
- 录用日期: 2022-12-08
- 出版日期: 2023-07-20

Liver transplantation for treating refractory hepatic inflammatory myofibroblastic tumor: A case report

1.
Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing 210008, China
2.
Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
3.
Department of Hepatobiliary and Pancreatic Surgery, Medical School of Southeast University Nanjing Drum Tower Hospital, Nanjing 210008, China

Research funding:

Youth Project of National Natural Science Foundation of China (82103135)

More Information

Corresponding author: XU Xiaoliang, xuxiaoliang1990@yeah.net (ORCID: 0000-0002-3617-6193)

摘要

- 肝移植 /
- 肿瘤, 肌组织 /
- 黄疸, 阻塞性
- Liver Transplantation /
- Neoplasms, Muscle Tissue /
- Jaundice, Obstructive

HTML全文

图 1 术前MRCP+增强检查结果

注：a, 3D-MRCP；b, T₁WI平扫；c, 动脉期强化；d, 静脉期强化。

Figure 1. Preoperative images of MRCP and enhanced MR

下载: 全尺寸图片幻灯片

图 2 术后肝肿物病理检查结果(HE染色，×100)

Figure 2. Postoperative pathological results of liver tumor (HE staining, ×100)

下载: 全尺寸图片幻灯片

图 3 术后10个月复查增强CT检查结果

注：a, 平扫；b, 动脉期强化；c, 静脉期强化。

Figure 3. Images of enhanced CT at ten months after operation

下载: 全尺寸图片幻灯片

参考文献(23)

[1]	GROS L, DEI TOS AP, JONES RL, et al. Inflammatory myofibroblastic tumour: State of the art[J]. Cancers (Basel), 2022, 14(15): 3662. DOI: 10.3390/cancers14153662.
[2]	JO VY, FLETCHER CD. WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition[J]. Pathology, 2014, 46(2): 95-104. DOI: 10.1097/PAT.0000000000000050.
[3]	JIA RX, ZHOU X, SHI ZK, et al. Recurrent vulvar angiomyofibroblastoma: A case report and literature review[J]. J Jilin Univ(Med Edit), 2023, 49(1): 193-197. DOI: 10.13481/j.1671-587X.20230125. 贾荣霞, 周旭, 石贽堃, 等. 外阴血管肌纤维母细胞瘤复发1例报告及文献复习[J]. 吉林大学学报(医学版), 2023, 49(1): 193-197. DOI: 10.13481/j.1671-587X.20230125.
[4]	SIEMION K, RESZEC-GIELAZYN J, KISLUK J, et al. What do we know about inflammatory myofibroblastic tumors?-A systematic review[J]. Adv Med Sci, 2022, 67(1): 129-138. DOI: 10.1016/j.advms.2022.02.002.
[5]	GUO XF, GAO C, SUN H, et al. Epidemiological characteristics and diagnosis analysis of liver inflammatory myofibroblastic tumor in recent 20 years in China[J]. Chin J Clin Rat Drug Use, 2017, 10(21): 34-6. DOI: 10.15887/j.cnki.13-1389/r.2017.21.017. 郭祥峰, 高超, 孙华, 等. 我国近20年肝脏炎性肌纤维母细胞瘤流行病学特征及诊治分析[J]. 临床合理用药杂志, 2017, 10(21): 34-36. DOI: 10.15887/j.cnki.13-1389/r.2017.21.017.
[6]	LIANG YR, HUANG SH, BAO SY, et al. Hepatic inflammatory myofibroblastic tumors: Analysis of 24 cases[J]. World Chin J of Dig, 2014, 22(20): 2952-2956. 梁泳荣, 黄孙辉, 鲍思扬, 等. 肝脏炎性肌纤维母细胞瘤24例[J]. 世界华人消化杂志, 2014, 22(20): 2952-2956.
[7]	FARAJ W, AJOUZ H, MUKHERJI D, et al. Inflammatory pseudo-tumor of the liver: a rare pathological entity[J]. World J Surg Oncol, 2011, 9: 5. DOI: 10.1186/1477-7819-9-5.
[8]	SHIMODAIRA Y, SUGAWARA K, FUKUDA S, et al. Aggressive inflammatory myofibroblastic tumor without anaplastic lymphoma kinase gene rearrangement in the rectum with liver metastasis[J]. Intern Med, 2020, 59(4): 495-499. DOI: 10.2169/internalmedicine.3686-19.
[9]	ELPEK GÖ. Inflammatory myofibroblastic tumor of the liver: A diagnostic challenge[J]. J Clin Transl Hepatol, 2014, 2(1): 53-57. DOI: 10.14218/JCTH.2013.00023.
[10]	SHEN P, TANG SS. Ultrasound features of hepatic inflammatory myofibroblastic tumor: a report of 4 cases[J]. J Clin Hepatol, 2018, 34(5): 1042- 1045. DOI: 10.3969/j.issn.1001-5256.2018.05.023. 沈鹏, 唐少珊. 4例肝炎性肌纤维母细胞瘤的超声表现特征分析[J]. 临床肝胆病杂志, 2018, 34(5): 1042-1045. DOI: 10.3969/j.issn.1001-5256.2018.05.023.
[11]	LIU XW, WANG TT, WEN H, et al. Pathological features of hepatic inflammatory myofibroblastoma and the CT and MRI imaging signs[J]. Chin J CT and MRI, 2022, 20(2): 84-86. DOI: 10.3969/j.issn.1672-5131.2022.02.028. 刘晓伟, 王婷婷, 温辉, 等. 肝脏炎性肌纤维母细胞瘤病理特点及CT、MRI影像征象分析[J]. 中国CT和MRI杂志, 2022, 20(2): 84-86. DOI: 10.3969/j.issn.1672-5131.2022.02.028.
[12]	STRAINIENE S, SEDLECKAITE K, JARASUNAS J, et al. Complicated course of biliary inflammatory myofibroblastic tumor mimicking hilar cholangiocarcinoma: A case report and literature review[J]. World J Clin Cases, 2021, 9(21): 6155-6169. DOI: 10.12998/wjcc.v9.i21.6155.
[13]	WU G, CHEN XC. Hepatic inflammatory myofibroblastic tumor[J]. Chin J of Pract Surg, 2013, 33(9): 749-751. DOI: 1005-2208(2013)09-0749-03. 吴刚, 陈旭春. 肝脏炎性肌纤维母细胞瘤诊断和治疗[J]. 中国实用外科杂志, 2013, 33(9): 749-751. DOI: 1005-2208(2013)09-0749-03.
[14]	SCHULZ MS, GU W, SCHNITZBAUER AA, et al. Liver transplantation as a cornerstone treatment for acute-on-chronic liver failure[J]. Transpl Int, 2022, 35: 10108. DOI: 10.3389/ti.2022.10108.
[15]	AMER A, WILSON CH, MANAS DM. Liver transplantation for unresectable malignancies: Beyond hepatocellular carcinoma[J]. Eur J Surg Oncol, 2019, 45(12): 2268-2278. DOI: 10.1016/j.ejso.2019.07.024.
[16]	GAO SQ, BAO YJ, LUO JS. Inflammatory myofibroblastic tumor of the hilar bile duct: A case report and literature review[J]. Front Surg, 2022, 9: 928669. DOI: 10.3389/fsurg.2022.928669.
[17]	HENEGHAN MA, KAPLAN CG, PRIEBE CJ Jr, et al. Inflammatory pseudotumor of the liver: a rare cause of obstructive jaundice and portal hypertension in a child[J]. Pediatr Radiol, 1984, 14(6): 433-435. DOI: 10.1007/BF02343436.
[18]	KIM HB, MALLER E, REDD D, et al. Orthotopic liver transplantation for inflammatory myofibroblastic tumor of the liver hilum[J]. J Pediatr Surg, 1996, 31(6): 840-842. DOI: 10.1016/s0022-3468(96)90148-7.
[19]	DASGUPTA D, GUTHRIE A, MCCLEAN P, et al. Liver transplantation for a hilar inflammatory myofibroblastic tumor[J]. Pediatr Transplant, 2004, 8(5): 517-521. DOI: 10.1111/j.1399-3046.2004.00206.x.
[20]	KIM SJ, KIM WS, CHEON JE, et al. Inflammatory myofibroblastic tumors of the abdomen as mimickers of malignancy: imaging features in nine children[J]. AJR Am J Roentgenol, 2009, 193(5): 1419-1424. DOI: 10.2214/AJR.09.2433.
[21]	BERUMEN J, MCCARTY P, MO J, et al. Combined liver transplant and pancreaticoduodenectomy for inflammatory hilar myofibroblastic tumor: Case report and review of the literature[J]. Pediatr Transplant, 2017, 21(2): e12846. DOI: 10.1111/petr.12846.
[22]	SETYA A, JASWINDER K, ANAND G, et al. Liver transplant as treatment modality for inflammatoryMyofibroblastic tumor of the liver[J]. Acad J Gastroenterol Hepatol, 2020, 2(1): 1-4. DOI: 10.33552/ajgh.2020.02.000527.
[23]	COSTA CM, NETO JS, BENAVIDEZ MR, et al. Liver transplantation for hilar inflammatory myofibroblastic tumor: Case report and review of the literature[J]. Pediatr Transplant, 2022: e14445. DOI: 10.1111/petr.14445.