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胆囊颈原发性不典型性上皮样血管内皮瘤1例报告

杨婕 夏成茂 刘喆 朱萌 舍雅莉

引用本文:
Citation:

胆囊颈原发性不典型性上皮样血管内皮瘤1例报告

DOI: 10.3969/j.issn.1001-5256.2023.07.023
基金项目: 

兰州市城关区2021年科技计划项目 (2021JSCX0029)

伦理学声明:本例报道已获得患者及家属知情同意。
利益冲突声明:本文不存在任何利益冲突。
作者贡献声明:杨婕负责论文设计,资料分析,撰写论文;夏成茂、刘喆、朱萌参与收集分析病例资料;舍雅莉负责指导撰写文章并最后定稿。
详细信息
    通信作者:

    舍雅莉,sheyali@sina.com (ORCID:0000-0001-6373-0746)

Primary atypical epithelioid hemangioendothelioma of the neck of the gallbladder: A case report

Research funding: 

Science and Technology Plan Projects for 2021 in Chengguan District, Lanzhou City (2021JSCX0029)

More Information
  • 图  1  胆囊颈EHE的病理形态及免疫组化结果

    注:a,肿瘤细胞呈条索状分布,部分肿瘤细胞的胞质内可见空泡形成(HE染色,×400);b,肿瘤细胞呈上皮样,具有明显异型性,细胞体积大,胞浆丰富,部分细胞胞核增大呈空泡状,其间见大小不等的血管腔(HE染色,×400);c,肿瘤细胞CAMTA1(+)(免疫组化染色,×200);d,肿瘤细胞TFE-3(+)(免疫组化染色,×200);e,肿瘤细胞CD31(+)(免疫组化染色,×200);f,肿瘤细胞FⅧ-R-Ag(+)(免疫组化染色,×200);g,肿瘤细胞CKp(+)(Envision法,×200);h,肿瘤细胞Vimentin(+)(Envision法,×200);i,肿瘤细胞Ki-67阳性指数>60%(免疫组化染色,×200)。

    Figure  1.  Pathological morphology and immunohistochemical results for epithelioid hemangioendothelioma of neck of gallbladder

  • [1] ROSENBERG A, AGULNIK M. Epithelioid hemangioendothelioma: Update on diagnosis and treatment[J]. Curr Treat Options Oncol, 2018, 19(4): 19. DOI: 10.1007/s11864-018-0536-y.
    [2] GUO Q, XUE J, XU L, et al. The clinical features of epithelioid hemangioendothelioma in a Han Chinese population: A retrospective analysis[J]. Medicine (Baltimore), 2017, 96(26): e7345. DOI: 10.1097/MD.0000000000007345.
    [3] SIGALA F, GALYFOS G, KONIARIS E, et al. Epithelioid hemangioendothelioma of the retroperitoneum - a rare vascular tumor[J]. Vasa, 2021, 50(4): 312-316. DOI: 10.1024/0301-1526/a000898.
    [4] REQUENA L, KUTZNER H. Hemangioendothelioma[J]. Semin Diagn Pathol, 2013, 30(1): 29-44. DOI: 10.1053/j.semdp.2012.01.003.
    [5] WEISS SW, ENZINGER FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma[J]. Cancer, 1982, 50(5): 970-981. DOI: 10.1002/1097-0142(19820901)50:5<970::aid-cncr2820500527>3.0.co;2-z.
    [6] JUNG H, KIM HN, JANG Y, et al. CAMTA-1 expression in 24 cases of hepatic epithelioid hemangioendothelioma in a single institute: Diagnostic utility for differential diagnosis from hepatic angiosarcoma[J]. In Vivo, 2019, 33(6): 2293-2297. DOI: 10.21873/invivo.11736.
    [7] WU X, LI B, ZHENG C, et al. Clinical characteristics of epithelioid hemangioendothelioma: a single-center retrospective study[J]. Eur J Med Res, 2019, 24(1): 16. DOI: 10.1186/s40001-019-0375-8.
    [8] AMIN RM, HIROSHIMA K, KOKUBO T, et al. Risk factors and independent predictors of survival in patients with pulmonary epithelioid haemangioendothelioma. Review of the literature and a case report[J]. Respirology, 2006, 11(6): 818-825. DOI: 10.1111/j.1440-1843.2006.00923.x.
    [9] DEYRUP AT, TIGHIOUART M, MONTAG AG, et al. Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases[J]. Am J Surg Pathol, 2008, 32(6): 924-927. DOI: 10.1097/pas.0b013e31815bf8e6.
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出版历程
  • 收稿日期:  2022-10-24
  • 录用日期:  2022-11-24
  • 出版日期:  2023-07-20
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