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肌少症对肝移植患者预后影响的研究进展
DOI: 10.3969/j.issn.1001-5256.2021.06.052
利益冲突声明：所有作者均声明不存在利益冲突。
作者贡献声明：李宇轩负责拟定写作思路、搜集相关文献以及撰写原稿；刘文亚负责论文修改及最终定稿审查。
Research advances in the value of sarcopenia in the prognosis of patients after liver transplantation
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摘要: 肌少症常伴发于晚期肝癌等终末期肝病患者，这种并发症与肝移植围术期的病死率相关，而有限的肝脏资源要求传统评估体系进一步改善移植队列的生存率。通过对骨骼肌病理机制和诊治策略的汇总评价，可以看出骨骼肌作为一种有效预测患者生存的身体成分参数，配合肝功能评估量表可优化移植队列顺序和手术效益。其相关死亡的具体机制并不清晰，诊断指标逐渐精简，尚无可以逆转病死率的治疗策略。根据现有文献，肌少症是确定肝移植候选人的重要参数之一。Abstract: Sarcopenia is often observed in patients with end-stage liver disease such as advanced liver cancer. This complication is associated with mortality rate in the perioperative period of liver transplantation, and limited liver resources require traditional evaluation systems to further improve the survival rate of the transplant cohort. Summarization and evaluation of skeletal muscular pathology and diagnosis and treatment strategies show that as a body composition parameter that can effectively predict the survival of patients, skeletal muscle can help to optimize the sequence of transplantation cohorts and surgical benefits in combination with liver function assessment scale. The specific mechanism of related death remains unclear, the diagnostic indicators are gradually streamlined, and there is no treatment strategy that can reverse the mortality rate. Based on the existing literature, sarcopenia is one of the important parameters for determining candidates for liver transplantation.
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Key words:
- Sarcopenia /
- Liver Transplantation /
- Prognosis
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