Significance of detecting the function of platelet in the patients with chronic hepatitis B and liver cirrhosis after hepatitis B
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摘要: 探讨慢性乙肝及乙肝肝硬化患者循环血中血小板的功能状态。应用ELISA定量法检测GMP 14 0 、PAIgG A M、PLT、MPV、FN、PC八项指标在各组患者循环血中含量。除PC外 ,各项指标均有较好的变化规律 ,如血小板表面相关抗体增加 ,血小板减少 ,血小板平均容积增大等。若能动态监测 ,对判断病情及指导治疗有重要意义。Abstract: To investigate the function of platelet in the circulation of chronic hepatitis B and cirrhosis after hepatitis B. The content of eight indexes included GMP- 140 PAIgG. A. M, PLT, MPV, FN, PC in cirrculation of every group patients were detected by ELISA quantity test. The better change rule was in every index except PC These indexes were generally analysed the function of platelet in the cirrculation of patients were really reflected. These results play an important role in diagnosis and treatment of patients studied.
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[1] MetzelaarMJ, cleversHC .Lysosomalmembraneglycoproteins.inplateiets[J]ThrombHaemost, 1994, 68∶378. [2]吴国新, 阮长耿血小板颗粒膜蛋白的研究进展[J]中华血液学杂志, 1994, 15 (3) ∶162 [3]蒋惠源, 吴国新, 张威, 等特发性血小板减少性紫癜患者血浆中血小板颗粒膜蛋白140自身抗体的研究[J]中华血液学杂志, 1994, 15 (3) ∶120 [4]张新华, 吕伟成, 吕世远, 等肝硬变和肝癌患者血浆GMP 140、PC、Fb和D D的意义[J]华人消化杂志, 1998, 6 (4) ∶356 [5] 阮长耿血小板—基础与临床[M]上海科技出版社1987124-127 [6]HofelerH .FibronectionandfacterⅧrelatedantigeninlivercirrho sisandfailure[J]JclimchemclimBiochem, 1985, 22∶15. [7]ReillyJT .1mmno-enzymaticdetectionoffibronetioninnormalandpathologicalhaematopoietictissue[J]BrJHaematol, 1985, 59∶497. [8]叶晓光, 冯国强各型乙肝患者血小板功能的检测[J]临床肝胆病杂志, 1996, 12 (2) ∶101 [9] 廖耀庭纤维结合蛋白测定及临床意义[J]中华医学检验杂志, 1987, 10 (4) ∶241
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