IL-18在病毒性肝炎发病机制中的作用

谭友文; 吴建成

IL-18在病毒性肝炎发病机制中的作用

详细信息

中图分类号: R512.6
计量
- 文章访问数: 3278
- HTML全文浏览量: 2
- PDF下载量: 919
- 被引次数: 0
出版历程
- 出版日期: 2005-02-20

摘要

HTML全文

参考文献(20)

[1] OkamuraH , TsutsuiH , KomatsuT , etal.CloningofanewcytokinethatinducesIFN -productionbyTcells[J].Nature, 1995, 378 (1) ∶88-91.

[2] NakanishiK , YoshimotoT , TsutsuiH , etal.Interleukin-18regulatesbothTh1andTh2responses[J].AnnuRevImmunol, 2001, 19 (2) ∶423-474.

[3] AllerMA , AriasJL , NavaMP , etal.PosttraumaticInflammationIsaComplexResponseBasedonthePathologicalExpressionoftheNervous, Immune, andEndocrineFunctionalSystems[J].ExperimentalBiologyandMedicine, 2004, 229 (1) ∶170-181.

[4] SaeedA , Jortani, SumanthD , etal.StrategiesforDevelopingBiomarkersofHeartFailure[J].ClinicalChemistry, 2004, 50 (2) ∶265-278.

[5] NowakM , GainesGC , RosenbergJ, etal.LPSinducedliverinjuryinDgalactosminesensitizedmicerequiressecretededTNFalphaandtheTNFp55receptor[J].AmJPhsiolRegulIntegrCompPhysiol, 2000, 278 (8) ∶1202-1209.

[6] JosephsMD , BahjatFR , Fukuzukak, etal.LipopolysaccharideandDgalac tosamineinducedhepaticinjuryismediatedbyTNFalphaandnotbyFalligand[J].AmJPhysiolRegulIntegrCompPhysiol, 2000, 278 (9) ∶1196-1201.

[7] TsutsuiH , MatsuiK , OkamuraH , etal, Pathophysiologicalrolesofinter leukin-18ininflammatoryliverdiseases[J].ImmunolRev, 2000, 174 (1) ∶192-209.

[8] H .NakaeaYJ, ZhengaH , WadaaK , etal.EndobInvolvementofIL -18andSolubleFasinPatientswithPostoperativeHepaticFailure[J].EurSurgRes, 2003, 35 (1) ∶61-66.

[9] EiichiroY , ToshihiroH , KazuhiroN , etal.IL -8andIL -10inacutehepatitis∶Serumgamma-interferon-inducingfactor (IL -18) andIL -10levelsinpatientswithacutehepatitisandfulminanthepaticfailure[J].JGastroenterologyandHepatology, 2002, 17 (1) ∶285-294.

[10] McGuinnessPH , PainterD , DaviesS , etal.IncreasesinintrahepaticCD68positivecells, MAC387positivecells, andproinflammatorytokines (particularlyIL -18) inchronichepatitisCinfection[J].Gut, 2000, 46 (2) ∶260-269.

[11]文维群, 章廉, 肖红, 等乙型肝炎病毒感染者IL -18基因的转录及表达[J].中华医学杂志, 2001, 81 (9) ∶655-658.

[12] KiminoriK , KazuhiroK .Interleukin-18InhibitsHepatitisBVirusReplicationintheLiversofTransgenicMice[J].JVirol, 2002, 76 (21) ∶10702-10707.

[13] JiaHDuJZhuS , etalClinicalobservationofserumIL -18, IL -10andsIL -2RlevelsinpatientswithchronichepatitisCpre-andpostan tiviraltreatment[J].ChinMedJ (Engl) , 2003, 116 (4) ∶605-8.

[14] ArbuthnotP , CapovillaA , KewM .PutativeroleofhepatitisBvirusXproteininhepatocarcinogenesis∶effectsonapoptosis, DNArepair, mitogen-activatedproteinkinaseandJAK/STATpathways[J].JGastroenterolHepatol, 2000, 15 (2) ∶357-368.

[15] ManigoldT , B ckerU , ChenJ , etal.HepatitisBcoreantigenstimulatesinterleukin-18production[J].JMedVirol, 2003, 71 (1) ∶31-40.

[16]ChenJZ , ZhuHH , LiuKZ , etal.EnhancingcellularimmuneresponsetoHBVMDNAvaccineinmicebycodeliveryofinterleukin-18recombi nant[J].ZhejiangUnivSci, 2004, 5 (4) ∶467-471.

[17] KiminoriK , KazuhiroK , StefanW , etal.ActivatedIntrahepaticAntigen-PresentingCellsInhibitHepatitisBVirusReplicationintheLiverofTransgenicMicel[J].TheJournalofImmunology, 2002, 169 (16) ∶5188-5195.

[18] NicholasAS , PeterHMcG .InsightsintothePathobiologyofHepatitisCVirus-AssociatedCirrhosisAnalysisofIntrahepaticDifferentialGeneEx pression[J].AmericanJournalofPathology, 2002, 160 (20) ∶641-654.

[19] FinottoS , SieblerJ, HausdingM , etalSeverehepaticinjuryininter leukin18 (IL -18) transgenicmice∶akeyroleforIL -18inregulatinghepatocyteapoptosisinvivo[J].Gut, 2004, 53 (3) ∶392-400.

[20] UrushiharaN , IwagakiH , YagiT .Elevationofseruminterleukin-18levelsandactivationofKupffercellsinbiliaryatresia[J].PediatrSurg, 2000, 35 (3) ∶446-459.

施引文献

资源附件(0)

访问统计