对1例隐匿性慢性乙型肝炎的病例分析

李春霞; 潘怀强; 李延军; 徐光华; 陈延平; 冯继红; 魏华; 曾庆磊

对1例隐匿性慢性乙型肝炎的病例分析

延安大学附属医院感染病科

详细信息

中图分类号: R512.62
计量
- 文章访问数: 3381
- HTML全文浏览量: 10
- PDF下载量: 1107
- 被引次数: 0
出版历程
- 出版日期: 2012-01-20

One case report of occult hepatitis B infection

摘要

摘要: <正>1病历资料患者男,38岁,司机,因"间断性右季肋区不适2年,加重2月余"就诊。2年前患者无明显诱因自觉肝区不适,在我院就诊时查乙型肝炎系列示:HBsAg阴性、抗-HBs阳性、HBeAg阴性、抗-HBe阳性、抗-HBc阳性,当时未行进一步诊治。2011年2月初患者无明显诱因,再次出现右季肋区不适,查乙型肝炎系列示:HBsAg阴性、抗-HBs阳性、HBeAg阴性、抗-HBe阳性、抗-HBc阳性,甲、丙、戊、丁型肝炎抗体、
- 肝炎,乙型,慢性 /
- DNA,病毒
- hepatitis B /
- chronic

HTML全文

参考文献(14)

[1] 中华医学会.慢性乙型肝炎防治指南 (2010年版) [J].临床肝胆病杂志, 2011, 27 (1) :I-XVI.

[2]Torbenson M, Thomas DL.Occult hepatitis B[J].LancetInfect Dis, 2002, 2 (8) :479-486.

[3]张玲, 张振华, 孙平, 等.慢性乙型肝炎病毒感染者家族隐匿性乙型肝炎病毒感染的调查[J].中华传染病杂志, 2010, 28 (3) :159-163.

[4]Kumar GT, Kazim SN, Kumar M, et al.Hepatitis B virusgenotypes and hepatitis B surface antigen mutations in fami-ly contacts of hepatitis B virus infected patients with occulthepatitis B virus infection[J].Gastroenterol Hepatol, 2009, 24 (4) :588-598.

[5]江红, 汤正好.隐匿性乙型肝炎[J].临床肝胆病杂志, 2004, 20 (5) :311-312.

[6]Marusawa H, Uemoto S, Hijikata M, et al.Latent hepatitis B vi-rus infection in healthy individuals with antibodies to hepatitis Bcore antigen[J].Hepatology, 2000, 31 (2) :488-495.

[7]Hou J, Wang Z, Cheng J, et al.Prevalence of naturally oc-curring surface gene variants of hepatitis B virus in nonimmu-nized surface antigen-negative Chinese carriers[J].Hepa-tology, 2001, 34 (5) :1027-1034.

[8]Jeantet D, Chemin I, Mandrand B, et al.Cloning and ex-pression of surface antigens from occult chronic hepatitis Bvirus infections and their recognition by commercial detectionassays[J].Med Virol, 2004, 73 (4) :508-515.

[9]Loriot MA, Marcellin P, Bismuth E, et al.Demonstration ofhepatitis B virus DNA by polymerase chain reaction in the se-rum and the liver after spontaneous or therapeutically inducedHBeAg to anti-HBe or HBsAg to anti-HBs seroconversionin patients with chronic hepatitis B[J].Hepatol, 1992, 15 (1) :32-36.

[10]Liu CJ, Chen DS, Chen PJ.Epidemiology of HBV infection in A-sian blood donors:emphasis on occult HBV infection and therole of NAT[J].Clin Virol, 2006, 36 (Suppl 1) :S33-S44.

[11]Liu CJ, Lo SC, Kao JH, et al.Transmission of occult hepati-tis B virus by transfusion to adult and pediatric recipients inTaiwan[J].Hepatol, 2006, 44 (1) :39-46.

[12]McClary H, Koch R, Chisari FV, et al.Inhibition of hepati-tis B virus replication during schistosoma mansoni infection intransgenic mice[J].Exp Med, 2000, 192 (2) :289-294.

[13]Doitsh G, Shaul Y.HBV transcription repression in responseto genotoxic stress is p53-dependent and abroganted bypX[J].Oncogene, 1999, 18 (52) :7506-7513.

[14]张振华, 赵西平, 夏剑波.隐匿性乙型肝炎病毒感染者血清表面抗体性质鉴定[J].中华肝脏病杂志, 2011, 19 (7) :506-510.

施引文献

资源附件(0)

访问统计