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Current development of liver transplantation in China
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摘要:
作为治疗各种终末期肝病唯一有效的方法,肝移植近年在国内发展迅速。叙述了肝移植在国内的最新发展成果,包括肝癌肝移植受者选择标准——杭州标准的确立;挽救性肝移植及降期治疗在肝癌肝移植中的最新应用;肝移植联合人工肝技术治疗急性重症肝衰竭的进展;活体肝移植技术创新和心脏死亡器官捐献移植在中国的突破性发展。面临器官短缺,应建立符合中国国情的科学规范的器官捐献体系,在造福于广大人民的同时也将进一步提升我国器官移植学界在国际上的声誉。
Abstract:As the only effective way for the treatment of end- stage liver disease, liver transplantation has been developed rapidly in China over recent years. The latest developments of liver transplantation in China are reviewed, including establishment of selection criteria for the liver cancer recipients of liver transplantation——Hangzhou Criteria; latest application of salvage liver transplantation and downstaging therapy in liver transplantation for liver cancer; progress in liver transplantation combined with artificial liver support system for treatment of severe acute liver failure; breakthrough in technology innovation of living donor liver transplantation and organ donation and transplantation after cardiac death in China. Facing the problem of organ shortage, a scientific and standardized organ donation system should be established in line with the national conditions of China, so as to benefit the people and further improve the reputation of China in the international organ transplant community.
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Key words:
- liver transplantation /
- liver neoplasms /
- liver failure
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[1] STARZL TE, MARCHIORO TL, VONKAULLA KN, et al.Homotransplantation of the liver in humans[J].Surg Gynecol Obstet, 1963, 117:659-676. [2] STARZL TE.The long reach of liver transplantation[J].Nat Med, 2012, 18 (10) :1489-1492. [3] MAZZAFERRO V, REGALIA E, DOCI R, et al.Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis[J].N Engl J Med, 1996, 334 (11) :693-699. [4]ZHENG SS, XU X, WU J, et al.Liver transplantation for hepatocellular carcinoma:Hangzhou experiences[J].Transplantation, 2008, 85 (12) :1726-1732. [5]FAN ST.Selection of HCC patients for liver transplantation:the Milan criteria, Hangzhou criteria and beyond[J].Hepatobiliary Pancreat Dis Int, 2008, 7 (3) :233-234. [6]AUDET M, PANARO F, PIARDI T, et al.Are the Hangzhou Criteria adaptable to hepatocellular carcinoma patients for liver transplantation in western countries?[J].Liver Transpl, 2009, 15 (7) :822-823. [7]HU Z, ZHOU J, XU X, et al.Salvage liver transplantation is a reasonable option for selected patients who have recurrent hepatocellular carcinoma after liver resection[J].PLoS One, 2012, 7 (5) :e36587. [8]LEI J, YAN L.Outcome comparisons among the Hangzhou, Chengdu, and UCSF criteria for hepatocellular carcinoma liver transplantation after successful downstaging therapies[J].J Gastrointest Surg, 2013.[Epub ahead of print] [9]LEE WM, STRAVITZ RT, LARSON AM.Introduction to the revised American association for the study of liver diseases position paper on acute liver failure 2011[J].Hepatology, 2012, 55 (3) :965-967. [10]CHAN G, TAQI A, MAROTTA P, et al.Long-term outcomes of emergency liver transplantation for acute liver failure[J].Liver Transpl, 2009, 15 (12) :1696-1702. [11]XU X, LIU X, LING Q, et al.Artificial liver support system combined with liver transplantation in the treatment of patients with acute-on-chronic liver failure[J].PLoS One, 2013, 8 (3) :e58738. [12]LING Q, XU X, WEI Q, et al.Downgrading MELD improves the outcomes after liver transplantation in patients with acute-onchronic hepatitis B liver failure[J].PLoS One, 2012, 7 (1) :e30322. [13] WU J, WANG W, ZHANG M, et al.Reconstruction of middle hepatic vein in living donor liver transplantation with modified right lobe graft:a single center experience[J].Transpl Int, 2008, 21 (9) :843-849. -
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