Research progress in association between interleukin-23 and liver diseases
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摘要: 白细胞介素(IL)23是近年来发现的细胞因子,越来越多的证据表明其在自身免疫性及炎症性疾病等的发生、发展过程中发挥着重要作用。近年来,国内外在IL-23与肝脏疾病的关系研究取得了一定进展。简述了IL-23的一般性质及生物学特性;对IL-23在乙型肝炎、丙型肝炎和肝细胞癌等疾病发生、发展中的作用进行了综述,以期临床医生对IL-23在肝脏疾病中的作用有更加深入的了解,未来能够为肝病患者提供更优化的治疗。Abstract: Interleukin 23( IL- 23) is a recently discovered cytokine,and growing evidence suggests that IL- 23 plays an important role in the development and progression of autoimmune diseases and inflammatory diseases. In recent years,certain research advances in association between IL- 23 and liver diseases have been achieved at home and abroad. General features and biological characteristics of IL- 23 are described,and its role in the development and progression of diseases such as hepatitis B,hepatitis C,and hepatocellular carcinoma is reviewed here,so that clinicians will have a deeper understanding of the effect of IL- 23 in liver diseases and provide optimized therapies for patients with liver diseases.
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Key words:
- liver diseases /
- interleukin-23 /
- review
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