-
摘要: <正>系统性淀粉样变性是由于淀粉样蛋白在全身细胞外组织间隙中沉积,从而破坏细胞和器官功能的疾病,约30%淀粉样变性累及肝脏[1]。肝淀粉样变性是一种罕见病,缺乏特征性的临床表现,因而极易误诊、漏诊[2]。1病例资料患者女性,64岁,因"腹部不适半年余,加重10余天"入院。患者半年前开始自觉腹部不适,两次就诊于外院,首次就
-
Key words:
- amyloidosis /
- liver diseases /
- biopsy /
- needles
-
[1] MERLINI G,BELLOTTI V.Molecular mechanisms of amyloidosis[J].N Engl J Med,2003,349(6):583-596. [2]ZHAO XY,JIA JD,WANG BE,et al.Clinical features of 30 cases of amyloidosis[J].Chin J Hepatol,2005,13(1):42-44.(in Chinese)赵新颜,贾继东,王宝恩,等.30例淀粉样变性患者的临床特点分析[J].中华肝脏病杂志,2005,13(1):42-44. [3]SIPE JD,BENSON MD,BUXBAUM JN,et al.Amyloid fibril protein nomenclature:2012 recommendations from the nomenclature committee of the international society of amyloidosis[J].Amyloid,2012,19(4):167-170. [4]PALLADINI G,MERLINI G.Systemic amyloidoses:what an internist should know[J].Eur J interm Med,2013,24(8):729-739. [5] PARK M,MUELLER P,KYLE R,et al.Primary(AL)hepatic amyloidosis:clinical features and natural history in 98 patients[J].Medicine(Baltimore),2003,82(5):291-298. [6] CLOUGH J,SHAH R.Primary amyloidosis presenting as common bile duct obstruction with cholangitis[J].ACG Case Rep J,2015,2(2):107-109. [7] LOIZOS S,CHRYSA TS,CHRISTOS GS.Amyloidosis:review and imaging findings[J].Semin Ultrasound CT,2014,35(3):225-239. [8]LAVATELLI F,ALBERTINI R,DI FONZO A,et al.Biochemical markers in early diagnosis and management of systemic amyloidoses[J].Clin Chem Lab Med,2014,52(11):1517-1531. [9] GIRNIUS S,SELDIN DC,SKINNER M,et al.Hepatic sponse after high-dose melphalan and stem cell transplantation in patients with AL amyloidosis associated liver disease[J].Haematologica,2009,94(7):1029-1032. [10]HU YL,PAN Y,XIN GJ,et al.Clinical diagnosis of patients with hepatic amyloid degeneration[J].J Clin Hepatol,2010,26(1):65-66.(in Chinese)胡玉琳,潘煜,辛桂杰,等.4例肝淀粉样变性的临床特点和分析[J].临床肝胆病杂志,2010,26(1):65-66.
本文二维码
计量
- 文章访问数: 1925
- HTML全文浏览量: 4
- PDF下载量: 473
- 被引次数: 0