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经内镜逆行胰胆管造影胆道金属支架置入治疗不可切除肝外胆道恶性梗阻的效果观察

徐刚

张沛欣, 边培育, 叶传涛, 郑煦暘, 范超, 张颖, 贾战生, 周云. HCV感染者直接抗病毒药物治疗前后CD8+T淋巴细胞衰老和功能相关指标的变化[J]. 临床肝胆病杂志, 2020, 36(7): 1496-1501. DOI: 10.3969/j.issn.1001-5256.2020.07.011.
引用本文: 张沛欣, 边培育, 叶传涛, 郑煦暘, 范超, 张颖, 贾战生, 周云. HCV感染者直接抗病毒药物治疗前后CD8+T淋巴细胞衰老和功能相关指标的变化[J]. 临床肝胆病杂志, 2020, 36(7): 1496-1501. DOI: 10.3969/j.issn.1001-5256.2020.07.011.
Zhang PeiXin, Bian PeiYu, Ye ChuanTao, Zheng XuYang, Fan Chao, Zhang Ying, Jia ZhanSheng, Zhou Yun. Changes in senescence-and function-related parameters of CD8+T cells after direct-acting antiviral treatment in patients with hepatitis C virus infection[J]. J Clin Hepatol, 2020, 36(7): 1496-1501. DOI: 10.3969/j.issn.1001-5256.2020.07.011.
Citation: Zhang PeiXin, Bian PeiYu, Ye ChuanTao, Zheng XuYang, Fan Chao, Zhang Ying, Jia ZhanSheng, Zhou Yun. Changes in senescence-and function-related parameters of CD8+T cells after direct-acting antiviral treatment in patients with hepatitis C virus infection[J]. J Clin Hepatol, 2020, 36(7): 1496-1501. DOI: 10.3969/j.issn.1001-5256.2020.07.011.

经内镜逆行胰胆管造影胆道金属支架置入治疗不可切除肝外胆道恶性梗阻的效果观察

DOI: 10.3969/j.issn.1001-5256.2018.02.023
详细信息
  • 中图分类号: R735

Clinical effect of biliary metal stent implantation via endoscopic retrograde cholangiopancreatography in treatment of unresectable malignant extrahepatic biliary obstruction

  • 摘要:

    目的探讨经内镜逆行胰胆管造影(ERCP)胆道金属支架置入对于肝外胆道恶性梗阻的临床疗效及安全性。方法收集2010年1月-2015年12月郑州大学第二附属医院收治的不可切除性肝外胆道恶性梗阻患者40例。根据手术方法不同分为经皮经肝胆管穿刺引流术(PTCD)组和ERCP组各20例。观察2组患者支架通畅期和生存期、术后临床疗效、术后并发症发生情况、术后住院时间等指标。计量资料组间比较采用t检验;计数资料组间比较采用χ2检验或校正的χ2检验。2组支架通畅期和生存期的比较采用Kaplan-Meier法对数秩检验。结果 ERCP组患者的支架通畅期[(225.6±52.5)d vs(156.3±44.5)d]、生存期[(335.6±42.5)d vs(225.5±42.5)d]较PTCD组均明显延长(t值分别为11.45、10.46,P值均<0.05)。ERCP组患者术后发生腹痛(7例)少于PTCD组(10例),差异有统计学意义(35.0%vs 50.0%,χ2=9.45,P<0.05)。ERCP组患者术后严重并发症发生率显著低于PTCD组(10.0%vs 30.0%,χ2=7.49,P...

     

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