Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases
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摘要: 目的探讨超声内镜(EUS)检查在胰腺占位性疾病中的应用价值。方法纳入2015年1月-2017年1月嘉兴学院附属第二医院诊治的可疑胰腺占位性疾病患者85例,以手术病理或随访结果作为金标准,评价EUS及EUS引导下穿刺活组织检查(EUS-FNA)在胰腺占位的应用价值。计数资料组间比较采用配对样本χ2检验。结果 EUS对胰腺占位的影像学检出率为96.7%(59/61),特异度为100%(24/24),准确率为97.6%(83/85);EUS在检出率和准确率上均明显优于腹部B超、CT和MRI(检出率:χ2=4.344、3.873、15.445;准确率:χ2=6.675、8.685、17.389,P值均<0.05)。EUS-FNA对肿瘤性占位的检出率和准确率分别为81.8%(45/55)、81.0%(47/58)。在手术明确病理的患者中,术前EUS-FNA检查的总体符合率为84.2%(16/19)。结论EUS较常规影像学检查对于胰腺占位具有更高的影像学准确率,EUS-FNA可进一步明确占位性质、病理类型,EUS可为胰腺肿瘤的...Abstract: Objective To investigate the value of endoscopic ultrasonography ( EUS) in the diagnosis of pancreatic space-occupying diseases. Methods A total of 85 patients with suspected pancreatic space-occupying diseases who were treated in The Second Affiliated Hospital of Jiaxing College from January 2015 to January 2017 were enrolled. Surgical pathological results or follow-up results were used as the gold standard for evaluating the value of EUS and EUS-guided fine needle aspiration ( EUS-FNA) in the diagnosis of pancreatic space-occupying diseases. The chi-square test was used for comparison of categorical data between groups. Results EUS had an imaging detection rate of 96. 7% ( 59/61) , a specificity of 100% ( 24/24) , and an accuracy rate of 97. 6% ( 83/85) in the diagnosis of pancreatic space-occupying diseases; EUS had significantly higher detection rate and accuracy rate than abdominal ultrasound, computed tomography, and magnetic resonance imaging ( detection rate: χ2= 4. 344, 3. 873, and 15. 445, all P < 0. 05; accuracy rate: χ2= 6. 675, 8. 685, and 17. 389, all P <0. 05) . EUS-FNA had a detection rate of 81. 8% ( 45/55) and an accuracy rate of 81. 0% ( 47/58) . Among the patients who underwent surgery to have pathological results, the overall coincidence rate of preoperative EUS-FNA was 84. 2% ( 16/19) . Conclusion Compared with conventional imaging examinations, EUS has a higher diagnostic accuracy for pancreatic space-occupying diseases, and EUS-FNA can further clarify the nature and pathological type of space-occupying lesions. EUS may help with the early diagnosis and treatment of pancreatic tumors.
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Key words:
- endoscopic ultrasonography /
- pancreatic neoplasms /
- biopsy, needle /
- dignosis
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