Importance of the clinical research on alcoholic hepatitis
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摘要:
酒精性肝炎(AH)是肝脏的一种无菌性炎症性损伤,大多发生在慢性肝病(脂肪肝、肝硬化)的基础上,因短期内大量饮酒所致肝病的急性恶化,是酒精性肝病严重的表现形式。AH的预后取决于治疗的时机和方法,肝功能可迅速恢复,也可迅速恶化至多脏器功能衰竭。不少临床医生还缺乏对AH的早期识别和及时处理的经验,主要原因是AH缺乏典型的临床表现,又缺少特异性的辅助检查,从而影响临床诊断,贻误治疗时机。因此,重视AH的临床研究,总结出临床真实世界的大数据,制订相应的专家共识已经势在必行。
Abstract:Alcoholic hepatitis ( AH) is a non-infectious inflammatory injury of the liver and often occurs on the basis of chronic liver dis-ease including fatty liver disease and liver cirrhosis. Acute exacerbation of liver disease due to heavy drinking within a short period of time isa severe manifestation of AH. The prognosis of AH depends on treatment timing and methods, and liver function can quickly recover or rap-idly deteriorate into multiple organ failure. Many clinicians lack the experience in early identification and timely treatment of AH, due to alack of typical clinical manifestations and specific auxiliary examinations, which affects clinical treatment, delays treatment, and exposessome AH patients to the risk of death. Therefore, it is imperative to conduct more clinical studies on AH, summarize real-world data, anddevelop expert consensus.
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Key words:
- hepatitis, alcoholic /
- diagnosis /
- editorial
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