饮酒对慢性乙型肝炎患者疾病进展和抗病毒治疗的影响

刘晨; 邢卉春; 成军; 杨松

doi:10.3969/j.issn.1001-5256.2019.03.003

饮酒对慢性乙型肝炎患者疾病进展和抗病毒治疗的影响

DOI: 10.3969/j.issn.1001-5256.2019.03.003

首都医科大学附属北京地坛医院肝病三科

基金项目:

北京市卫生系统高层次卫生技术人才培养计划(2015-3-108)；吴阶平医学基金会临床科研专项(LDWJPMF-105-201701)；国家重大科技专项经费资助(2017ZX10202201,2017ZX10202202)；

详细信息

中图分类号: R512.62;R575
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出版历程
- 收稿日期: 2019-01-14
- 出版日期: 2019-03-20

Influence of drinking on progression of chronic hepatitis B and outcome of antiviral therapy

Third Department of Hepatology, Beijing Ditan Hospital, Capital Medical University

Research funding:

摘要

摘要: HBV与酒精可以通过多种机制相互影响导致肝损伤。大量饮酒可以使慢性乙型肝炎(CHB)患者的疾病进展更为迅速且预后更差,同时严重影响抗病毒治疗效果和依从性。我国CHB患者饮酒的流行病学情况尚不明确,HBV与酒精的相互影响机制尚需进一步明确。临床上,仍需进一步规范CHB患者的戒酒管理,尽可能减轻酒精导致的肝损伤。
- 肝炎,乙型,慢性 /
- 肝疾病,酒精性 /
- 饮酒 /
- 流行病学 /
- 病理过程 /
- 治疗结果
Abstract: HBV can interact with alcohol in various ways to cause liver damage. Heavy drinking can accelerate the progression of chronichepatitis B and lead to a poorer prognosis; meanwhile, it can also affect the outcome and compliance in patients receiving antiviral therapy.The epidemiology of drinking in patients with chronic hepatitis B in China remains unclear, and further studies are needed to clarify themechanism of interaction between alcohol and HBV. Drinking management should be strengthened in patients with chronic hepatitis B inclinical practice, in order to alleviate liver injury induced by alcohol.
- hepatitis B, chronic /
- liver diseases, alcoholic /
- alcohol drinking /
- epidemiology /
- pathologic processes /
- treatment outcome

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参考文献(33)

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