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肝细胞癌患者微波消融治疗前后血清异常凝血酶原水平变化及临床意义

孙玉 张洪海 袁春旺 李聪 扈彩霞 崔石昌 张永宏 郑加生

孙玉, 张洪海, 袁春旺, 李聪, 扈彩霞, 崔石昌, 张永宏, 郑加生. 肝细胞癌患者微波消融治疗前后血清异常凝血酶原水平变化及临床意义[J]. 临床肝胆病杂志, 2019, 35(3): 542-546. DOI: 10.3969/j.issn.1001-5256.2019.03.018.
引用本文: 孙玉, 张洪海, 袁春旺, 李聪, 扈彩霞, 崔石昌, 张永宏, 郑加生. 肝细胞癌患者微波消融治疗前后血清异常凝血酶原水平变化及临床意义[J]. 临床肝胆病杂志, 2019, 35(3): 542-546. DOI: 10.3969/j.issn.1001-5256.2019.03.018.
Sun Yu, Zhang HongHai, Yuan ChunWang, Li Cong, Hu CaiXia, Cui ShiChang, Zhang YongHong, Zheng JiaSheng. Change in serum level of abnormal prothrombin after microwave ablation for hepatocellular carcinoma and its clinical significance[J]. J Clin Hepatol, 2019, 35(3): 542-546. DOI: 10.3969/j.issn.1001-5256.2019.03.018.
Citation: Sun Yu, Zhang HongHai, Yuan ChunWang, Li Cong, Hu CaiXia, Cui ShiChang, Zhang YongHong, Zheng JiaSheng. Change in serum level of abnormal prothrombin after microwave ablation for hepatocellular carcinoma and its clinical significance[J]. J Clin Hepatol, 2019, 35(3): 542-546. DOI: 10.3969/j.issn.1001-5256.2019.03.018.

肝细胞癌患者微波消融治疗前后血清异常凝血酶原水平变化及临床意义

DOI: 10.3969/j.issn.1001-5256.2019.03.018
基金项目: 

国家自然科学基金资助项目(81472328); 

详细信息
  • 中图分类号: R735.7

Change in serum level of abnormal prothrombin after microwave ablation for hepatocellular carcinoma and its clinical significance

Research funding: 

 

  • 摘要: 目的研究肝细胞癌(HCC)患者微波消融治疗前后血清异常凝血酶原(DCP)及AFP水平变化,并对HCC复发进行监测,探讨血清DCP、AFP水平与复发的关系。方法选择2015年12月-2018年2月在首都医科大学附属北京佑安医院住院治疗并经肝穿刺活组织病理检查确诊为HCC的患者76例,检测患者微波消融术前、术后、复发时血清DCP及AFP水平并进行分析。非正态分布的计量资料2组之间比较采用Mann-Whitney U检验,3组之间比较采用Kruskal-Wallis H检验; 2组样本的相关性检验采用Spearman相关分析。结果 HCC患者微波消融术后1周血清DCP及AFP与术前相比明显下降(Z值分别为6. 854、6. 246,P值均<0. 01),术后1个月血清DCP及AFP相比术前及术后1周进一步下降,差异均有统计学意义(DCP:Z值分别为11. 639、4. 786,AFP:Z值分别为10. 058、3. 812,P值均<0. 01)。76例HCC患者中59例出现肿瘤复发,复发时其血清DCP及AFP水平均高于术后1周及术后1个月,差异均有统计学意义(DCP:Z值分别为-...

     

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  • 收稿日期:  2018-10-08
  • 出版日期:  2019-03-20
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