自身免疫性肝炎临床治疗进展

金超; 潘洁露; 喻晓; 张海燕; 邢练军

doi:10.3969/j.issn.1001-5256.2019.10.044

自身免疫性肝炎临床治疗进展

DOI: 10.3969/j.issn.1001-5256.2019.10.044

上海中医药大学附属龙华医院脾胃病二科

基金项目:

国家自然科学青年基金(81503512)；上海市进一步加快中医药事业发展三年行动计划(2018年-2020年)(ZY(2018-2020)CCCX-2002-03)；

详细信息

中图分类号: R575.1
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- 被引次数: 0
出版历程
- 收稿日期: 2019-05-27
- 出版日期: 2019-10-20

Advances in the clinical treatment of autoimmune hepatitis

Second Department of Gastroenterology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Research funding:

摘要

摘要: 自身免疫性肝炎(AIH)是一种发病原因不明的由自身免疫介导的慢性进行性肝脏炎症性疾病。目前治疗AIH的主要目的是缓解症状,改善肝功能及病理组织异常,减慢向肝纤维化的进展。由于其容易复发,预后差异大,给治疗带来难度。近年来,AIH治疗方法主要有标准免疫抑制疗法,标准治疗无效的替代疗法或二线疗法,减轻副作用的中医药疗法,以及AIH末期或严重暴发性AIH的肝移植抢救疗法。对上述AIH治疗方法进行了系统综述,以期为临床应用提供参考。
- 肝炎,自身免疫性 /
- 补充疗法 /
- 肝移植 /
- 治疗学
Abstract: Autoimmune hepatitis(AIH) is an autoimmune-mediated chronic progressive liver inflammatory disease with unknown pathogenesis. The main purpose of AIH treatment at present is to relieve symptoms,improve liver function and pathological abnormalities,and slow down the progression to liver fibrosis. Easy recurrence and a large difference in prognosis bring difficulties to the treatment of this disease. In recent years,AIH treatment methods mainly include standard immunosuppressive therapy,substitutive therapy or second-line therapy for ineffective standard therapy,traditional Chinese medicine treatment with reduced side effects,and liver transplantation rescue therapy for end-stage AIH or severe fulminant AIH. This article reviews the above treatment methods for AIH,in order to provide a reference for clinical application.
- hepatitis,autoimmune /
- complementary therapies /
- liver transplantation /
- therapeutics

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参考文献(28)

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