自身免疫性肝炎发病机制的研究现状

曹亦楠; 周桂琴; 王宪波; 李斌; 冯颖; 胡超群

doi:10.3969/j.issn.1001-5256.2019.10.045

自身免疫性肝炎发病机制的研究现状

DOI: 10.3969/j.issn.1001-5256.2019.10.045

1. 首都医科大学附属北京地坛医院中西医结合一科
2. 北京中医药大学东直门医院

基金项目:

北京市医院管理局临床医学发展专项经费资助(ZYLX201707)；

详细信息

中图分类号: R575.1
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出版历程
- 收稿日期: 2019-05-20
- 出版日期: 2019-10-20

Research advances in the pathogenesis of autoimmune hepatitis

First Department of Integrated Traditional Chinese and Western Medicine,Beijing Ditan Hospital,Capital Medical University

Research funding:

摘要

摘要: 自身免疫性肝炎是一种病因尚不明确的、进行性的慢性炎症性肝病。目前,遗传易感性和环境因素是普遍公认的自身免疫性肝炎病因学因素。近年来随着研究的不断深入,免疫细胞、免疫因子、肝移植及药物等病因学因素也逐渐受到关注,阐述了近5年的相关最新研究成果。
- 肝炎,自身免疫性 /
- 疾病遗传易感性 /
- 环境因素诱发疾病 /
- 免疫因子类 /
- 化学性与药物性肝损伤 /
- 肝移植
Abstract: Autoimmune hepatitis(AIH) is a progressive chronic inflammatory liver disease with unknown etiology. At present,genetic susceptibility and environmental factors are universally recognized as the etiological factors for AIH. With the deepening of research in recent years,other etiological factors,such as immune cells,immune factors,liver transplantation,and drugs,have attracted more and more attention. This article briefly describes related research findings in the past five years.
- hepatitis,autoimmunity /
- genetic predisposition to disease /
- disorders of environmental origin /
- immunologic factors /
- chemical and drug induced liver injury /
- liver transplantation

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参考文献(50)

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