自身免疫生态学因素在自身免疫性肝炎发病机制中的作用

陈杰; 黄春洋; 单晶; 刘燕敏

doi:10.3969/j.issn.1001-5256.2019.10.046

自身免疫生态学因素在自身免疫性肝炎发病机制中的作用

DOI: 10.3969/j.issn.1001-5256.2019.10.046

首都医科大学附属北京佑安医院肝病免疫科

基金项目:

北京市属医院科研培育计划(PX2019062)；首都卫生发展科研专项青年项目(首发2014-4-2183)；丰台区卫生系统科研项目(2016-62)；

详细信息

中图分类号: R575.1
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出版历程
- 收稿日期: 2019-05-27
- 出版日期: 2019-10-20

Role of autoimmune ecological factors in the pathogenesis of autoimmune hepatitis

Department of Hepatology and Immunology,Beijing YouAn Hospital,Capital Medical University

Research funding:

摘要

摘要: 自身免疫性肝炎(AIH)是一种病因未明的慢性肝脏炎症性疾病,目前认为遗传和环境因素都参与AIH的发生。环境暴露对AIH发病的影响是至关重要的。自身免疫生态学是研究个体与环境之间的相互作用,以及个体与环境之间失平衡的发生及对自身免疫性疾病发展的促进机制的学科。就近年来自身免疫生态学在AIH发病机理研究进展作一综述。
- 肝炎,自身免疫性 /
- 环境暴露 /
- 生态学
Abstract: Autoimmune hepatitis(AIH) is a chronic liver inflammatory disease with unknown etiology,and at present,both genetic and environmental factors are thought to be involved in the pathogenesis of AIH. Environmental exposure has an important impact on the development of AIH. Autoimmune ecology is the study of the interactions between individuals and their environment,the development of imbalance between individuals and environment,and the mechanism of such imbalance in promoting the development of autoimmune disease. This article reviews the research advances in the role of autoimmune ecology in the pathogenesis of AIH.
- hepatitis,autoimmune /
- enviromental exposure /
- ecologys

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参考文献(26)

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