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Child-Pugh评分和ALBI分级预测经肝动脉化疗栓塞治疗不可切除肝细胞癌预后的价值比较

王哲轩 王恩鑫 夏冬东 白苇 王秋和 袁洁 李晓梅 牛静 郭文刚 李凯 殷占新 韩国宏

王哲轩, 王恩鑫, 夏冬东, 白苇, 王秋和, 袁洁, 李晓梅, 牛静, 郭文刚, 李凯, 殷占新, 韩国宏. Child-Pugh评分和ALBI分级预测经肝动脉化疗栓塞治疗不可切除肝细胞癌预后的价值比较[J]. 临床肝胆病杂志, 2020, 36(1): 113-117. DOI: 10.3969/j.issn.1001-5256.2020.01.025.
引用本文: 王哲轩, 王恩鑫, 夏冬东, 白苇, 王秋和, 袁洁, 李晓梅, 牛静, 郭文刚, 李凯, 殷占新, 韩国宏. Child-Pugh评分和ALBI分级预测经肝动脉化疗栓塞治疗不可切除肝细胞癌预后的价值比较[J]. 临床肝胆病杂志, 2020, 36(1): 113-117. DOI: 10.3969/j.issn.1001-5256.2020.01.025.
Wang ZheXuan, Wang EnXin, Xia DongDong, Bai Wei, Wang QiuHe, Yuan Jie, Li XiaoMei, Niu Jing, Guo WenGang, Li Kai, Yin ZhanXin, Han GuoHong. Value of Child-Pugh score versus albumin-bilirubin grade in predicting the prognosis of unresectable hepatocellular carcinoma treated by transarterial chemoembolization[J]. J Clin Hepatol, 2020, 36(1): 113-117. DOI: 10.3969/j.issn.1001-5256.2020.01.025.
Citation: Wang ZheXuan, Wang EnXin, Xia DongDong, Bai Wei, Wang QiuHe, Yuan Jie, Li XiaoMei, Niu Jing, Guo WenGang, Li Kai, Yin ZhanXin, Han GuoHong. Value of Child-Pugh score versus albumin-bilirubin grade in predicting the prognosis of unresectable hepatocellular carcinoma treated by transarterial chemoembolization[J]. J Clin Hepatol, 2020, 36(1): 113-117. DOI: 10.3969/j.issn.1001-5256.2020.01.025.

Child-Pugh评分和ALBI分级预测经肝动脉化疗栓塞治疗不可切除肝细胞癌预后的价值比较

DOI: 10.3969/j.issn.1001-5256.2020.01.025
详细信息
  • 中图分类号: R735.7

Value of Child-Pugh score versus albumin-bilirubin grade in predicting the prognosis of unresectable hepatocellular carcinoma treated by transarterial chemoembolization

  • 摘要: 目的在经肝动脉化疗栓塞术(TACE)治疗的肝功能良好的肝细胞癌患者中,评估并比较Child-Pugh评分和ALBI分级对患者总生存情况的预测能力。方法回顾性收集2010年1月-2014年12月在空军军医大学西京消化病医院接受TACE治疗的不可切除185例HCC患者,收集患者的流行病学资料(年龄、性别、病因等),实验室检查资料(血常规、肝肾功能、凝血功能等),以及影像学检查资料(肿瘤大小、数目等),计算总生存时间,根据其基线状态以及实验室检查结果计算Child-Pugh评分和ALBI分级。使用Child-Pugh评分和ALBI评分进行危险分层,采用Kaplan-Meier绘制生存曲线,log-rank检验对总生存时间进行分析比较。Cox回归模型进行危险因素分析。通过依时ROC曲线分析和C指数比较2种评分预测生存情况的能力。结果根据ChildPugh评分,5分患者的中位生存时间及95%可信区间(95%CI)为25. 3(20. 1~30. 5)个月; 6分患者的中位生存时间为8. 6(7. 5~16. 9)个月,2者生存时间比较差异有统计学意义(P=0. 002);根据ALBI评分,1级的...

     

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  • 收稿日期:  2019-11-08
  • 出版日期:  2020-01-20
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