Splenic marginal zone lymphoma with pancytopenia as the first presentation: A case report
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摘要: <正>脾边缘区淋巴瘤(splenic marginal zone lymphoma,SMZL)是指原发于脾脏的B淋巴细胞性非霍奇金淋巴瘤。SMZL的发病率低,国内以全血细胞减少为首发表现的SMZL报道较少。为提高临床医务人员对SMZL的认识,现将本院诊治的1例报道如下。1病例资料患者女性,76岁,以"腹胀、纳差1年,全血细胞减少3 d"为主诉于2016年6月23日于本院就诊。1年前曾于本院就诊,患者无明显诱因出现腹胀,伴有纳差,无腹痛、腹泻,无畏寒发
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关键词:
- 淋巴瘤,B细胞,边缘区 /
- 脾 /
- 脾切除术 /
- 全血细胞减少
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Key words:
- lymphoma,B-cell,marginal zone /
- the spleen /
- splenectomy /
- pancytopenia
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[1] ARCAINI L,BESSON C,FRIGENI M,et al. Interferon-free antiviral treatment in B-cell lymphoproliferative disorders associated with hepatitis C virus infection[J]. Blood,2016,128(21):2527-2532. [2] FENSKE TS,HAMADANI M,COHEN JB,et al. Allogeneic hematopoietic cell transplantation as curative therapy for patients with non-Hodgkin lymphoma:Increasingly successful application to older patients[J]. Biol Blood Marrow Transplant,2016,22(9):1543-1551. [3] GROTH CL,NEVEL KS,GWATHMEY KG,et al. Splenic marginal zone lymphoma:An indolent malignancy leading to the development of neurolymphomatosis[J]. Muscle Nerve,2017,55(3):440-444. [4] YI S,YAN Y,XIONG W,et al. Distinct clinical characteristics draw a new prognostic model for splenic marginal zone lymphoma in HBV high prevalent region[J]. Oncotarget,2017,8(58):98757-98770. [5] SAADOUN D,SUAREZ F,LEFRERE F,et al. Splenic lymphoma with villous lymphocytes,associated with type II cryoglobulinemia and HCV infection:A new entity?[J]. Blood,2005,105(1):74-76. [6] MATUTES E,OSCIER D,MONTALBAN C,et al. Splenic marginal zone lymphoma proposals for a revision of diagnostic,staging and therapeutic criteria[J]. Leukemia,2008,22(3):487-495. [7] KALPADAKIS C,PANGALIS GA,SACHANAS S,et al. No evidence of splenic disease in patients with splenic marginal zone lymphoma undergoing splenectomy for autoimmune hemolytic anemia after monotherapy with rituximab[J]. Leuk Lymphoma,2016,57(11):2705-2708. [8] ARCAINI L,LAZZARINO M,COLOMBO N,et al. Splenic marginal zone lymphoma:Aprognostic model for clinical use[J].Bood,2006,107(12):4643-4649. [9] CHACN JI,MOLLEJO M,MUOZ E,et al. Splenic marginal zone lymphoma:Clinical characteristics and prognostic factors in a series of 60 patients[J]. Blood,2002,100(5):1648-1654. [10] YAN YT,YI SH,QIU LG. Advances in molecular genetics pathogenesis of splenic marginal zone lymphoma[J]. Chin J Hematol,2016,37(4):348-352.(in Chinese)阎禹廷,易树华,邱录贵.脾边缘区淋巴瘤发病机制研究进展[J].中华血液学杂志,2016,37(4):348-352. [11] HU Y,CHEN Y,WANG LH,et al. Identification of splenic marginal zone lymphoma from B lymphoproliferative disorders by flow cytometry[J]. J Exp Hematol,2014,22(2):349-356.(in Chinese)胡旸,陈艳,王丽华,等.用流式细胞术从B淋巴增殖性疾病中鉴别脾边缘带淋巴瘤[J].中国实验血液学杂志,2014,22(2):349-356. [12] BU F,FENG Q,WANG WY,et al. Splenic marginal zone lymphoma:A case report[J/CD]. Chin Arch General Surg(Electronic Version),2017,11(6):426-427.(in Chinese)卜凡,冯强,王文洋,等.脾边缘区B细胞淋巴瘤一例[J/CD].中华普通外科学文献(电子版),2017,11(6):426-427. [13] KALPADAKIS C,PANGALIS GA,VASSILAKOPOULOS TP,et al. Treatment of splenic marginal zone lymphoma:Should splenectomy be abandoned?[J]. Leuk Lymphoma,2014,55(7):1463-1470. [14] SALIDO M,BARC,OSCIER D,et al. Cytogenetic aberrations and their prognostic value in a series of 330 splenic marginal zone B-cell lymphomas:A multicenter study of the Splenic B-Cell Lymphoma Group[J]. Blood,2010,116(9):1479-1488. [15] ARCAINI L,VARETTONI M,BOVERI E,et al. Distinctive clinical and histological features of Waldenstrm’s macroglobulinemia and splenic marginal zone lymphoma[J]. Clin Lymphoma Myeloma Leuk,2011,11(1):103-105. [16] DU XF,MA ZP,LIN GS,et al. CT diagnosis and differentiation of nodular/mass-type hepatic lymphoma[J]. J Clin Hepatol,2017,33(8):1492-1496.(in Chinese)杜晓峰,马周鹏,林观生,等.6例肝脏结节/肿块型淋巴瘤患者的CT诊断及鉴别[J].临床肝胆病杂志,2017,33(8):1492-1496. [17] TSIMBERIDOU AM,CATOVSKY D,SCHLETTE E,et al. Outcomes in patients with splenic marginal zone lymphoma and marginal zone lymphoma treated with rituximab with or without chemotherapy or chemotherapy alone[J]. Cancer,2006,107(1):125-135. [18] STARR AG,CAIMI PF,FU PF,et al. Splenic marginal zone lymphoma:Excellent outcomes in 64 patients treated in the rituximab era[J]. Hematology,2017,22(7):405-411. [19] ELSE M,MARN-NIEBLA A,de la CRUZ F,et al. Rituximab,used alone or in combination,is superior to other treatment modalities in splenic marginal zone lymphoma[J]. Br J Haematol,2012,159(3):322-328. [20] KOOT AW,VISSCHER AP,HUITS RM. Remission of splenic marginal zone lymphoma in a patient treated for hepatitis B:A case of HBV-associated lymphoma[J]. Acta Clin Belg,2015,70(4):301-303. [21] KALPADAKIS C,PANGALIS GA,DIMITRIADOU E,et al. Mutation analysis of IgVH genes in splenic marginal zone lymphomas:Correlation with clinical characteristics and outcome[J].Anticancer Res,2009,29(5):1811-1816.
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