深圳地区出租车司机非酒精性脂肪性肝病患病现状分析

黄海燕; 韦荣新; 何广营; 曾辉苑

doi:10.3969/j.issn.1001-5256.2020.03.028

深圳地区出租车司机非酒精性脂肪性肝病患病现状分析

DOI: 10.3969/j.issn.1001-5256.2020.03.028

1. 深圳市龙华区人民医院全科门诊
2. 深圳市龙华区人民医院检验科

详细信息

中图分类号: R575.5
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出版历程
- 收稿日期: 2019-09-10
- 出版日期: 2020-03-20

Prevalence of nonalcoholic fatty liver disease in taxi drivers in Shenzhen,China

General Clinic,Shenzhen Longhua District People's Hospital

摘要

摘要: 目的了解深圳地区出租车司机非酒精性脂肪性肝病（NAFLD）的患病现状及其相关指标异常情况,为科学防治NAFLD提供依据。方法选取2018年5月-2019年6月来深圳市龙华区人民医院体检的出租车司机1752例,分别检测BMI、血压、空腹血糖（FPG）、总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL）、低密度脂蛋白胆固醇（LDL）、ALT、AST及尿酸（UA）等指标,并行肝脏B超检查,分析NAFLD患病率与各项生化指标的关系。计量资料2组间比较采用t检验,计数资料2组间比较采用χ2检验。结果出租车司机NAFLD患病率为51. 66%（905/1752）,其中男性为57. 94%（770/1329）,高于女性的31. 91%（135/423）,差异有统计学意义（χ2=9. 209,P=0. 027）。NAFLD出租司机的BMI、血脂、血压、FPG及UA异常率均高于非NAFLD出租车司机,差异均有统计学意义（χ2值分别为5. 894、7. 126、8. 045、8. 909、10. 373; P值分别为0. 04...
- 非酒精性脂肪性肝病 /
- 汽车驾驶 /
- 危险因素
Abstract: Objective To investigate the prevalence of nonalcoholic fatty liver disease( NAFLD) and related abnormal indicators among taxi drivers in Shenzhen,China,and to provide a basis for scientific prevention and treatment of fatty liver disease. Methods A total of1752 taxi drivers who underwent physical examination in Shenzhen Longhua District People's Hospital from May 2018 to June 2019 were selected,and related indicators were measured,including body mass index( BMI),blood pressure,fasting plasma glucose( FPG),total cholesterol( TC),triglyceride( TG),high-density lipoprotein( HDL),low-density lipoprotein( LDL),alanine aminotransferase( ALT),aspartate aminotransferase( AST),and uric acid( UA). Liver ultrasound examination was also performed. The association between the prevalence rate of NAFLD and various biochemical parameters was analyzed. The t-test was used for comparison of continuous data between two groups,and the chi-square test was used for comparison of categorical data between two groups. Results The prevalence rate of NAFLD among the taxi drivers was 51. 66%( 905/1752),and male drivers had a significantly higher prevalence rate than female drivers[57. 94%( 770/1329) vs 31. 91%( 135/423),χ2= 9. 209,P = 0. 027]. The taxi drivers with NAFLD had significantly higher abnormal rates of BMI,blood lipids,blood pressure,FPG,and UA than those without NAFLD( χ2= 5. 894,7. 126,8. 045,8. 909,and 10. 373,P = 0. 047,0. 035,0. 030,0. 028,and 0. 018). The taxi drivers with a BMI of ≥28 kg/m2 had a significantly higher prevalence rate of NAFLD than those with a BMI of 24. 0-27. 9 kg/m2 or a BMI of < 24 kg/m2( male: χ2= 7. 904 and 18. 624,P = 0. 035 and 0. 008; female: χ2= 8. 613 and 31. 635,P = 0. 029 and 0. 006). The taxi drivers with working years of > 15 years had a significantly higher prevalence rate of NAFLD than those with working years of 11-15 years,5-10 years,and < 5 years( male: χ2= 9. 781,13. 546,and 18. 052,P = 0. 024,0. 012,and 0. 008; female: χ2= 7. 052,9. 847,and 12. 157,P = 0. 036,0. 023,and 0. 016). Conclusion There is a high prevalence rate of NAFLD among taxi drivers in Shenzhen,and male drivers have a higher prevalence rate than female drivers. The prevalence rate of NAFLD is associated with the abnormal rates of hyperlipidemia,obesity,hyperglycemia,and hyperuricemia and the working years in driving.
- non-alcoholic fatty liver disease /
- automobile driving /
- risk factors

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参考文献(17)

[1] CHALASANI N,YOUNOSSI Z,LAVINE JE,et al. The diagnosis and management of nonalcoholic fatty liver disease:Practice guideline on the American Association for the Study of Liver Diseasesm[J]. Hepatology,2018,67(1):328-357.

[2] MIAO YX,WANG F,QIAO LM,et al. Clinical study of Atorvastatin combined with enteral nutrition in the treatment of senile non-alcoholic fatty liver with metabolic syndrome[J]. China Med Herald,2019,16(10):80-83.(in Chinese)缪艳霞，王芳，乔良美，等．阿托伐他汀联合肠内营养治疗老年非酒精性脂肪肝伴代谢综合征的临床研究[J]．中国医药导报，2019,16(10):80-83.

[3] SETO WK,YUEN MF. Nonalcoholic fatty liver disease in Asia:Emerging perspectives[J]. J Gastroenterol,2017,52(2):164-174.

[4] National Workshop on Fatty Liver and Alcoholic Liver Disease,Chinese Society of Hepatology,Chinese Medical Association;Fatty Liver Expert Committee,Chinese Medical Doctor Association. Guidelines of prevention and treatment for nonalcoholic fatty liver disease:A 2018 update[J]. J Clin Hepatol,2018,34(5):947-957.(in Chinese)中华医学会肝病学分会脂肪肝和酒精性肝病学组，中国医师协会脂肪性肝病专家委员会．非酒精性脂肪性肝病防治指南(2018年更新版)[J]．临床肝胆病杂志，2018,34(5):947-957.

[5] Writing Group of 2010 Chinese Guidelines for the Management of Hypertension. 2010 Chinese guidelines for the management of hypertension[J]. Chin J Hypertension,2011,19(8):701-743.(in Chinese)中国高血压防治指南修订委员会．中国高血压防治指南2010[J]．中华高血压杂志，2011,19(8):701-743.

[6] Working Group of Obesity in China. Guidelines for prevention and control of overweight and obesity in Chinese adults[J].Acta Nutrimenta Sinica,2004,26(1):1-4.(in Chinese)中国肥胖问题工作组．中国成人超重和肥胖症预防与控制指南(节录)[J]．营养学报，2004,26(1):1-4.

[7] DING L,CHEN JX,ZUO X,et al. Analysis on prevalence of fatty liver and its influencing factors of community residents in Wuhu City[J]. Chin J Dis Control Prev,2017,21(6):635-637.(in Chinese)丁蕾，陈婧鑫，左翔，等．芜湖市社区居民脂肪肝患病现状及影响因素分析[J]．中华疾病控制杂志，2017,21(6):635-637.

[8] MENG YL,ZHANG HY,SONG BG,et al. An investigation of the prevalence rate of fatty liver disease among people undergoing physical examination in Tangshan,China[J]. J Clin Hepatol,2017,33(12):2376-2380.(in Chinese)孟昱林，张海艳，宋宝国，等．唐山市体检人群脂肪肝患病率调查分析[J]．临床肝胆病杂志，2017,33(12):2376-2380.

[9] DING F,QIN YM,CAO QY,et al. Analysis of distribution characteristics and risk factors of non alcoholic fatty liver in healthy population of Xianning city[J]. Chin Nurs Res,2017,31(4):490-492.(in Chinese)丁芳，秦雨萌，曹群英，等．咸宁市健康体检人群非酒精性脂肪肝病的分布特征及危险因素分析[J]．护理研究，2017,31(4):490-492.

[10] HAN XJ. Investigation and analysis of the prevalence and related factors of fatty liver disease[J]. J Continuing Med Education,2016,30(3):75-76.(in Chinese)韩秀娟．脂肪肝患病率及相关因素的调查分析[J]．继续医学教育，2016,30(3):75-76.

[11] HUANG LY,SUN D,JIANG BJ,et al. Investigation and analysis of non-alcoholic fatty liver disease in medical examination population in a certain area of Tianjin[J]. Med Inf,2019,32(4):99-103.(in Chinese)黄玲玉，孙东，蒋本君，等．天津市某区域体检人群非酒精性脂肪肝调查分析[J]．医学信息，2019,32(4):99-103.

[12] WANG XR,WANG XR,GUO CL,et al. Investigation and analysis on the prevalence and risk factors of fatty liver disease in physical examination population of Baotou City[J].Mod Digest Interv,2015,20(3):239-242.(in Chinese)王小瑞，王晓荣，郭春林．等．包头市体检人群脂肪肝的患病率及危险因素调查分析[J]．现代消化及介入诊疗，2015,20(3):239-242.

[13] HART-UNGER S,ARAO Y,HAMILTON KJ,et al. Hormone signaling and fatty liver in females:Analysis of estrogen receptorαmutant mice[J]. Int J Obes(Lond),2017,41(6):945-954.

[14] RUAN JW,GAO LJ,LIANG XF,et al. An investigation of the prevalence rate of nonalcoholic fatty fiver disease in the population undergoing physical examination in Haikou,China[J]. J Clin Hepatol,2018,34(9):1925-1928.(in Chinese)阮建文，高丽娟，梁雄飞，等．海口地区体检人群非酒精性脂肪性肝病患病率调查分析[J]．临床肝胆病杂志，2018,34(9):1925-1928.

[15] CHEN JL,CHEN QP,ZENG SS. Study on the correlation between liver function index and blood lipid in patients with nonalcoholic fatty liver disease[J]. Med Inf,2017,30(15):185-186.(in Chinese)陈贱兰，陈前萍，曾顺生．非酒精性脂肪肝患者肝功能酶学指标与血脂检测结果相关性研究[J]．医学信息，2017,30(15):185-186.

[16] HAN J. Prevalence of nonalcoholic fatty liver disease,risk factor analysis and clinical study on its relationship with atherosclerosis[D]. Jinan:Shandong University,2019.(in Chinese)韩洁．非酒精性脂肪肝患病率调查、危险因素分析及与动脉硬化关系的临床研究[D]．济南:山东大学，2019.

[17] CHEN SS,ZHONG SY,LIN YH,et al. Investigation on the prevalence of nonalcoholic fatty liver disease in monastic of Putuoshan temple,Zhejiang Province[J]. Chin J Rural Med Pharm,2019,26(15):49-50.(in Chinese)陈守顺，钟素亚，林永红，等．浙江普陀山寺院僧尼非酒精性脂肪肝患病现状调查[J]．中国乡村医药，2019,26(15):49-50.

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