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经颈静脉肝内门体分流术治疗慢加急性肝衰竭患者肝硬化急性失代偿的效果及安全性分析

郭帅 韩国宏

郭帅, 韩国宏. 经颈静脉肝内门体分流术治疗慢加急性肝衰竭患者肝硬化急性失代偿的效果及安全性分析[J]. 临床肝胆病杂志, 2020, 36(4): 818-822. DOI: 10.3969/j.issn.1001-5256.2020.04.022.
引用本文: 郭帅, 韩国宏. 经颈静脉肝内门体分流术治疗慢加急性肝衰竭患者肝硬化急性失代偿的效果及安全性分析[J]. 临床肝胆病杂志, 2020, 36(4): 818-822. DOI: 10.3969/j.issn.1001-5256.2020.04.022.
Guo Shuai, Han GuoHong. Safety and efficacy of transjugular intrahepatic portosystemic shunt in treatment of acute decompensated cirrhotic events in patients with acute-on-chronic liver failure[J]. J Clin Hepatol, 2020, 36(4): 818-822. DOI: 10.3969/j.issn.1001-5256.2020.04.022.
Citation: Guo Shuai, Han GuoHong. Safety and efficacy of transjugular intrahepatic portosystemic shunt in treatment of acute decompensated cirrhotic events in patients with acute-on-chronic liver failure[J]. J Clin Hepatol, 2020, 36(4): 818-822. DOI: 10.3969/j.issn.1001-5256.2020.04.022.

经颈静脉肝内门体分流术治疗慢加急性肝衰竭患者肝硬化急性失代偿的效果及安全性分析

DOI: 10.3969/j.issn.1001-5256.2020.04.022
详细信息
  • 中图分类号: R575.3;R575.2

Safety and efficacy of transjugular intrahepatic portosystemic shunt in treatment of acute decompensated cirrhotic events in patients with acute-on-chronic liver failure

  • 摘要: 目的研究经颈静脉肝内门体分流术(TIPS)治疗慢加急性肝衰竭(ACLF)患者肝硬化急性失代偿事件的安全性及有效性。方法回顾性选取2008年6月-2017年12月于空军军医大学消化病医院住院并接受TIPS治疗的35例伴有肝硬化急性失代偿事件的ACLF患者,通过倾向性评分的方法按照1∶1的比例与接受内科治疗的患者(35例)进行匹配,收集患者临床、实验室及影像学资料。连续型变量两组间比较采用t检验或Mann-Whitney U检验。分类变量两组间比较采用χ2检验。使用logistic回归模型分析影响患者疾病进程的危险因素,采用Kaplan-Meier方法估计累积生存概率,运用Cox回归模型分析影响患者生存的危险因素,以及竞争风险模型比较随访期间肝性脑病发生率。结果接受TIPS治疗的患者中,病情好转者20例,病情稳定或恶化者15例;内科治疗组中,病情好转者11例,病情恶化或稳定者24例,TIPS治疗组较多患者病情得到改善(χ2=4. 69,P=0. 03)。logistic回归模型调整了性别、年龄后,相对于内科治疗,TIPS治疗更有利于患者病情的改善...

     

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  • 期刊类型引用(5)

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    2. 王迎迎. 乙型肝炎肝硬化急性恶化患者慢加急性肝衰竭的发生情况及预后分析. 当代医学. 2022(12): 31-34 . 百度学术
    3. 王晖,赵亚刚,李素英. 艾灸联合利福昔明预防乙肝肝硬化患者TIPS术后肝性脑病发生的临床观察. 云南中医中药杂志. 2022(08): 73-76 . 百度学术
    4. 王潇,陈拥军,姚勇,杜恒. 经颈静脉肝内门体分流术的临床应用现状. 四川医学. 2021(10): 1055-1058 . 百度学术
    5. 郭武辉,张华. 血清T淋巴细胞亚群检测在肝硬化合并真菌性血流感染中的诊断价值. 陕西医学杂志. 2021(12): 1570-1572+1576 . 百度学术

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  • 收稿日期:  2019-12-17
  • 出版日期:  2020-04-20
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