内脂素与非酒精性脂肪性肝病患者甲状腺功能异常的关系

任仕萍; 马臻棋; 王学红

doi:10.3969/j.issn.1001-5256.2020.06.042

内脂素与非酒精性脂肪性肝病患者甲状腺功能异常的关系

DOI: 10.3969/j.issn.1001-5256.2020.06.042

1. 青海大学研究生院
2. 青海大学附属医院消化内科

基金项目:

青海省消化系统疾病临床医学研究中心(2019-SF-L3)；

详细信息

中图分类号: R575.5
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出版历程
- 收稿日期: 2019-12-20
- 出版日期: 2020-06-20

Association of visfatin with thyroid dysfunction in patients with nonalcoholic fatty liver disease

Graduate School of Qinghai University
Department of Gastroenterology,Qinghai University Affiliated Hospital

Research funding:

摘要

摘要:
目前研究发现,内脂素参与了非酒精性脂肪性肝病(NAFLD)的脂质代谢过程,约25%的NAFLD患者伴甲状腺功能异常。内脂素还被发现通过自分泌或者旁分泌途径参与自身免疫调节,这与甲状腺作为人体的内分泌腺,参与调节全身各系统存在一定关联。通过文献回顾初步探究内脂素与NAFLD患者甲状腺功能异常的关系,提示内脂素的检测有助于早期发现NAFLD患者甲状腺功能异常。
- 非酒精性脂肪性肝病 /
- 烟酰胺磷酸核糖基转移酶 /
- 甲状腺激素类
Abstract:
Recent studies have found that visfatin is involved in lipid metabolism in patients with nonalcoholic fatty liver disease( NAFLD),and about 25% of NAFLD patients have thyroid dysfunction. It has also been found that visfatin is involved in autoimmune regulation through the autocrine or paracrine pathways,which is associated with the involvement of the thyroid gland in autoimmune regulation of the body. This article preliminarily explores the association of visfatin with thyroid dysfunction in NAFLD patients and points out that the measurement of visfatin may help with the early identification of thyroid dysfunction in NAFLD patients.
- non-alcoholic fatty liver disease /
- nicotinamide phosphoribosyltransferase /
- thyroid hormones

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参考文献(40)

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