胰液中循环游离DNA甲基化异常在胰腺癌早期诊断中的应用

周艳; 宁波

doi:10.3969/j.issn.1001-5256.2020.09.054

胰液中循环游离DNA甲基化异常在胰腺癌早期诊断中的应用

DOI: 10.3969/j.issn.1001-5256.2020.09.054

周艳,
宁波

重庆医科大学附属第二医院消化内科

基金项目:

重庆市卫健委高端医学后备人才项目(2016HBRC003)；

详细信息

中图分类号: R735.9
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出版历程
- 出版日期: 2020-09-20

Application of abnormal cell-free DNA methylation in pancreatic juice in the early diagnosis of pancreatic cancer

Zhou Yan,
Ning Bo

Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University

Research funding:

摘要

摘要:
胰腺癌是一种起病隐匿、恶性程度极高、诊断困难的消化系统肿瘤,早期诊断是提高胰腺癌患者生存率、改善预后的关键。介绍了胰液中循环游离DNA甲基化异常与胰腺癌早期诊断的相关研究的进展,认为胰液中循环游离DNA甲基化检测有望成为胰腺癌早期诊断的有效手段。
- 胰腺肿瘤 /
- 胰液 /
- DNA甲基化 /
- 早期诊断
Abstract:
Pancreatic cancer is a digestive system tumor with insidious onset,high malignancy,and difficult diagnosis,and early diagnosis is the key to improving the survival rate and prognosis of patients with pancreatic cancer. This article introduces the research advances in abnormal methylation of cell-free DNA in pancreatic juice and the early diagnosis of pancreatic cancer,and it is believed that the detection of cell-free DNA methylation in pancreatic juice may be an effective method for the early diagnosis of pancreatic cancer.
- pancreatic neoplasms /
- pancreatic juice /
- DNA methylation /
- early diagnosis

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参考文献(33)

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